PPT-Review of the Molecular Biology of Genes in Eukaryotes

Split genes Exons and introns Chromatin structure and states Epigenetics 122114 1 Classification by nucleus Prokaryotes Organisms whose cells lack a nucleus Bacteria and Archaea. Over the past decade an ever growing arsenal of techniques has helped researchers dissect the innermost secrets of the cell and develop new ways to detect and attack disease These techniques also have been used to produce vast amounts of once rare d PeregrinoUriarte Jorge Herna ndezLo pez Gloria YepizPlascencia b Centro de Investigaciones Biolo gicas del Noroeste CIBNOR Unidad Hermosillo Centenario Norte 53 Col Prados del Centenario Hermosillo Sonora CP 83260 Mexico Centro de Investigacio n e /2008/08/unbearable-lightness-of-aspen-part-1.html. Forams. Ciliates. Euglenozoans. Diatoms. COMMON. ANCESTOR . OF ALL LIFE. Land plants. Animals. Amoebas. Fungi. Red algae. Chlamydias. Green algae. (Mitochondria)*. ChemEng. 590B: Tissue Engineering. Lecture 2. January . 24. th. , . 2013. Animal Cell Structure. 2. Figure 6-2 . Molecular Biology of the Cell. (© Garland Science 2008). 3. The Central Dogma of Molecular Biology. Basic molecular biology techniques. Isolating nucleic acids. Cutting DNA into fragments. Ligating DNA fragments. Amplifying DNA fragments. Hybridization techniques. Genomics. Sequencing genomes. Analyzing genome sequences. Cancer Informatics (omics). David Boone. Outline. What is cancer and how is it different from other diseases?. Major players in tumor initiation (Understand one before many) . Oncogenes. Tumor suppressors. Basic molecular biology techniques. Isolating nucleic acids. Cutting DNA into fragments. Ligating DNA fragments. Amplifying DNA fragments. Hybridization techniques. Genomics. Sequencing genomes. Analyzing genome sequences. Cancer Informatics (omics). David Boone. Outline. What is cancer and how is it different from other diseases?. Major players in tumor initiation (Understand one before many) . Oncogenes. Tumor suppressors. . . Asst. . Prof. Dr. . Dalya. Basil Hanna. . . Molecular Biology of Cancer. Normal cells have a defined lifespan – they grow, divide, and die in an orderly fashion. A . What is life? Energy Self - replicating chemical system Cells compute: Can we decipher the biological hardware and software? (Andrianantoandro, Basu, Karig, Weiss (2006)) Some Overarching Organization Upgraded Lecture Note Series Jimma Universit y MOLECULAR BIOLOGY AND APPLIED GENETICS Lecture Note Series Democratic Republic of Ethiopia Ministry of Education and Ministry of Health The problem fa ;. . the. . study of . biology. at the . molecular. level.. Molecular biology. ;. . the. . study of . gene . structure and functions at the . molecular level. . to understand the molecular basis of hereditary, genetic variation, and the expression patterns of genes. . Biology and its complexity. Our own efforts here at . Colaba. campus: . A. brief introspection. CONCLUDING THOUGHTS . Where is Biology headed?. Biologists. Want to understand organisms and living systems. Biochemistry examines the rudimentary chemistry of life. Molecular biology studies the complex interactions among biological molecules. ASBMB publishes three prestigious research journals. ASBMB's journals publish original research in the fields of microbiology, molecular genetics, RNA-related research, proteomics, genomics, transcription, peptides, cell signaling, .