PPT-Red Blood Cell Disorders

Introduction Red blood cells are characterized by a biconcave shape aids efficient navigation through narrow vessels Surface antigens on red blood cells determine individual blood types Lack of nucleus and organelles enables high hemoglobin concentration for oxygen transport. Healthy red blood cells are round and they move through small blood vessels carrying oxygen to all parts of the body In SCD the red blood cells become hard and sticky and look like a Cshaped farm tool called a sickle Sickle cells die early which cau Shelby Engel and Sarah . Heins. . Blood transports necessary nutrients and hormones. Color, volume, viscosity, and . pH. RBCs/erythrocytes – transport oxygen. 4.2-6.3 million live 120 days. Hemoglobin typically 13.5-18g/100 ml for males, 12-16 for females. Read through these in your notes and in your text to make sure you understand the causes and/or symptoms . They will be on your Quiz. Hemolytic anemia. Aplastic Anemia. Thalassemia. Sickle Cell Anemia. Deena Iskander, Clinical Research Fellow. Centre for . Haematology. , Faculty of Medicine, Hammersmith Hospital, Imperial College London. Paediatric. . Haematology. and Bone Marrow Transplantation Unit, St Mary’s Hospital, Imperial College Healthcare NHS Trust, London, UK. CO binds to your . hemoglobin. , prevents oxygen from binding.  Can be fatal.   It is a "silent killer" as people often die in their sleep when a heater fails.. Carbon monoxide deaths are more likely to occur in winter. Infection. Human Immunodeficiency Virus. Genetics. Altered Immune Responses and Transplantation. Nursing Care of Clients with Lymph Disorders. Bacterial, Viral, and Fungal Infections: Prevention, Assessment and Interventions.. Infection. Human Immunodeficiency Virus. Genetics. Altered Immune Responses and Transplantation. Nursing Care of Clients with Lymph Disorders. Bacterial, Viral, and Fungal Infections: Prevention, Assessment and Interventions.. CP Biology. Genetic Disorders. Major types of genetic disorders:. Autosomal. Single genes. Multiple genes. Sex-linked. Chromosome abnormalities. Autosomal Disorders. Autosomal genetic disorders . are caused by alleles on autosomes (chromosomes other than the sex chromosomes). Toxic changes in neutrophils include all the following, except:. Cytoplasmic . basophilia. Large basophilic granules. Hypersegmentation. Cytoplasmic vacuoles. Dohle. bodies. Large granular lymphoma is associated with. Dr.Ayesha. . Junaid. MBBS,MCPS,FCPS.. Professor of Pathology. National . Hemovigilance. Coordinator . Supervisor & Program Director . Haematology. CPSP. Incharge. Blood transfusion services. Shifa. Most genes are carried on the ___________, ______ chromosomes other than the sex chromosomes. These disorders affect males and females ________ and are due to _____ mutations. Autosomal disorders can be divided into three groups based on the pattern of inheritance.. via an alternation . in the DNA . sequence. . Genetic . disorders can be caused by . a mutation in one . gene, . or . mutations . in multiple genes . or . a combination of gene mutations and environmental factors. . د.ميسم. مؤيد علوش . LEC.1. The white blood cells (leucocytes) may be divided into . two. . broad groups: the . phagocytes and the lymphocytes.. Phagocytes can themselves be subdivided into: . Incomplete Dominance . – blending of red and white to form the pink phenotype of the four o’clock flower . Chapter 14. Human Genetics. Sec. 14-1 Human Heredity. Human Traits. Pedigree. : chart that shows the genetic relationships within a family & how traits are passed from one generation to another.