PPT-RED CELL MEMBRANE DISORDERS

Dr Ali Khazaal Jumaa FIBMS Int Medicine FIBMS Hematology The red cell membrane RBC membrane plays a critical role in the maintenance of the biconcave shape and integrity of the red cell. . By Dr. . Vani. Gupta. 2. “Polarity” . of the . membrane. Na. +. K. +. Mg. 2+. Ca. 2+. H. +. HCO. 3. -. Cl. -. SO. 4. 2-. PO. 3. -. protein. inside. (in mM). 14. 140. 0.5. 10. -4. (pH 7.2). 10. Learning Objectives. outline the roles of membranes within cells and at the surface of cells. state that plasma (cell surface) membranes are partially permeable barriers. describe, with the aid of diagrams, the fluid mosaic model of membrane structure. . By Dr. . Vani. Gupta. 2. “Polarity” . of the . membrane. Na. +. K. +. Mg. 2+. Ca. 2+. H. +. HCO. 3. -. Cl. -. SO. 4. 2-. PO. 3. -. protein. inside. (in mM). 14. 140. 0.5. 10. -4. (pH 7.2). 10. and Transport. Cell Membrane. Cell membrane- also called the . Plasma Membrane. Separates the cell from its surrounding . environment.  . Helps maintain homeostasis which is keeping the internal conditions constant. Summary. How do materials get across a cell's membrane. ?. It depends on the type of substance. Summary. Non-polar materials or hydrophobic materials . do. cross easily, especially if small. Ex – CO. by . Vani. Gupta. Types of cell membrane transport. Factors affecting transport. . Cell membrane. Chemical gradient. Electrical gradient. Rate of transport. . Passive transport. Cell Membrane and Cell Wall:. . ALL. . cells have a . cell membrane. made of . proteins. and . lipids. . Cell Membrane. lipid bilayer. protein channel. protein . pump. Layer 1. Layer 2. SOME. cells have cell membranes . Cell Membrane and Cell Wall:. . ALL. . cells have a . cell membrane. made of . proteins. and . lipids. . Cell Membrane. lipid bilayer. protein channel. protein . pump. Layer 1. Layer 2. SOME. cells have cell membranes . Homeostasis & Cellular Transport. Function of the Cell Membrane:. Cell membrane separates the components of a cell from . its . environment. —surrounds the cell. “Gatekeeper” of the cell—regulates the flow of materials into and out of cell—. Cell Membrane. .. The cell membrane . Controls. what comes out and . in of the cell. . It also provides protection.. The composition is a double layered sheet called a . Bi-lipid layer. .. This lipid bi-layer is made up of two . Learning . Goal . Describe . the composition and function of the lipid bilayer in cell membranes.. Cell Membranes. Cell membranes. . are semipermeable so that nutrients can enter the cell and waste products can leave.. Structure. Main component is phospholipids that are arranged in a double layer (. bilayer. ). Has scattered proteins within the phospholipids. Regulate what enters/leaves cell. Function . Nucleus. Structure. What is the plasma membrane?. A flexible boundary between the cell and its environment which maintains . HOMEOSTASIS. within the cell. **Remember that . HOMEOSTASIS. is a state of balance/equilibrium within the cell.. primarily . of ______.. DNA. Protein. Carbohydrates. Phospholipids. 2. The . phospholipids in the cell membrane are arranged in a bilayer (double layer). How are the phospholipid molecules arranged in this bilayer?.