PPT-Cardiovascular outcomes

Silvio E Inzucchi Professor of Medicine Yale University School of Medicine New Haven CT USA 1 Disclosure Consultations and non financial support Boehringer Ingelheim Merck Janssen Novo Nordisk SanofiRegeron Intarcia Lexicon Poxel Takeda Eli Lilly. By: Jeremy Clark, Megan Windland, and Tiana Nater. Negative Effects of Cardiovascular disease. Eating foods that are high in saturated fats and cholesterol may cause plaque to form on artery walls. . CarTarDis. = . Car. diovascular . Tar. get . Dis. covery. Public-private partnership. 13 partners, 8 countries, project budget 8.0M Eur. Start 1 Oct 2013 for 4 years. (Coordinator). CarTarDis. FDA-Mandated CV Safety Trials. 1. TECOS. (Trial Evaluating Cardiovascular Outcomes with Sitagliptin). Clinical Outcomes with Antihyperglycemic Agents. 2. Clinical Outcomes with Sitagliptin. Study Design. Toni . Mustahsani. . Aprami. , dr., . Sp.PD. , Sp.JP. Department of Cardiology and Vascular Medicine. Cardiovascular Subdivision, Department of Internal Medicine. Hasan. . Sadikin. Hospital/Medical School, . CVOTs. 1. FDA CVOT Guidance—2008. Timeline of Major Diabetes. Outcomes Trials. 2. Blue. = Intensive vs standard control using same set of glucose-lowering agent(s). Purple. = Intensive control with a specific agent vs standard care. Cyrus Desouza, MD. October 22, 2017. Why?. 1A. Evaluate the effect of vitamin D supplementation on incident CVD in people with . pre-diabetes.. 1B. . Establish CVD . risk in people with . pre-diabetes, defined by the modern ADA criteria.. The Heart. The Heart. The Heart. A fist-sized, cone-shaped muscle (the myocardium) that beats, on average, 80 times per minute . . Divided into right and left sides by a muscular wall, the septum . . Diseases of the Cardiovascular System. 20.3 Cardiovascular and Lymphatic System Diseases Caused by Microorganisms. A. Endocarditis . 1. Inflammation of the endocardium . 2. Usually refers to an infection of the valves of the heart. David J Albrecht D.O.. Heart & Vascular 2018 Winter Conference. Cardiovascular risk . m. odification in relation to current diabetes management . therapies. Case study highlighting the therapeutic decisions . 1 Cardiovascular Disease in Virginia Cardiovascular disease is the most common cause of acute and chronic illness globally, in the U.S. and in Virginia. Affecting the heart and blood vessels, cardio TECOS Executive Committee MemberRury R. Holman, MB, ChBDiabetes Trials Unit, OCDEM Churchill Hospital, Oxford, United KingdomTECOS CoPrincipal Investigator andJoint Chair of TECOS Executive CommitteeR Claire S. . Duvernoy. , MD FACC. Female Specific. concerns. U.S. CVD Deaths. CVD. deaths. Salim S. Virani. Circulation. Heart Disease and Stroke Statistics—2020 Update: A Report From the American Heart Association, Volume: 141, Issue: 9, Pages: e139-e596.. Chapter 15. Heart Location. Close Up of Heart Wall. Cardiac Muscle Tissue. Cardiac Muscle Tissue (2). Superior & inferior Vena Cavae. Delivers deoxygenated blood to R. atrium from body. Coronary sinus drains heart muscle veins. A Scientific Statement From the AHA. Definition of . Cardiovascular-Kidney-Metabolic Syndrome (CKM). A systemic disorder characterized by pathophysiologic interactions among metabolic risk factors, chronic kidney disease, and the cardiovascular system, leading to multi-organ dysfunction and a high rate of adverse cardiovascular outcomes..