PPT-Evolution of Mitochondrial Genome Architecture in Nematodes

Sita Ping Department of Zoology Mentor Dr Dee Denver HHMI Summer 2010 Background Mitochondria organelle in eukaryotic cells that is responsible for energy production Electron transport chain located in the inner membrane of Mitochondria produces usable energy and in doing so gives off reactive oxygen species ROS. The Plot. Deepak . Purushotham. Hamid Reza . Hassanzadeh. Haozheng. . Tian. Juliette . Zerick. Lavanya. . Rishishwar. Piyush. . Ranjan. Lu Wang. The Outline. The Need & The Requirement. The Options. Cheam. Dee Denver, P. h. D. The Denver lab. Department of Zoology. HHMI Summer 2011. HHMI Project 2011. Investigating Possible Cryptic Species of . Xiphinema. . Nematodes through DNA Analysis. Investigating Possible Cryptic Species of . Stephen Okoth BSN, SRNA (Sr.). York . College of PA/. Wellspan. Health NAP . Objectives. Discuss the structure of the Mitochondrion. Discuss . the main . function . of the . Mitochondrion. Detecting and Diagnosing mitochondrial diseases. Stephen Okoth BSN, SRNA (Sr.). York . College of PA/. Wellspan. Health NAP . Objectives. Discuss the structure of the Mitochondrion. Discuss . the main . function . of the . Mitochondrion. Detecting and Diagnosing mitochondrial diseases. Key considerations:. Genes . Chromosomes. C value paradox. Gene regulation. Epigenetics. Transposable elements. DNA . ……..……..mRNA……….…….Protein . Plant . Estimated # genes. Arabidposis. Key considerations:. Genes . Chromosomes. C value paradox. Gene regulation. Epigenetics. Transposable elements. DNA . ……..……..mRNA……….…….Protein . Plant . Estimated # genes. Arabidposis. Fahad Alqahtani. Supervisor: Dr. Ion Măndoiu. Associate Advisors: Dr. Mukul Bansal & Dr. Derek Aguiar. Computer Science & Engineering Department. University of Connecticut. Outline. Background. What you need to know:. The major goals of the Human Genome Project.. How . prokaryotic genomes compare to eukaryotic genomes. .. Applications of bioinformatics to medicine, evolution, and health.. The activity and role of transposable elements and . Summary of Research Interests. Gene identification and genome annotation. The evolution of genome-sequence compositional properties. Models of protein evolution. The phylogeny of Bacteria. Measures of differentiation from genomic and . Mina . Marden. Mitochondrial DNA. Mitochondrial DNA. Entire genome: 3.0x10. 9. . bp. Mitochondrial genome: 16,569 . bp. How I compared it…. Which mitochondrial genomes?. Felis. . catus. Panthera. xxia@uottawa.ca. http://dambe.bio.uottawa.ca. Definitions. Genome: the . entire complement of genetic material carried by an individual. Transcriptome with two definitions:. the . entire set of . transcribable sequences from the genome (operationally all RNA sequences from annotated productive genes in a genome). Mitochondrial DNA Mitochondrial DNA (mtDNA) is DNA contained in the mitochondria in our cells - these are the energy - generating structures commonly referred to as the 'batteries' or 'powerhouses' [22]. The pattern of blocks was assessed to see whether theirarrangement in the ancestral genome prior to duplicationarrangement in the ancestral genome prior to duplicationequally parsimonious series Fahad Alqahtani and Ion Mandoiu. University of Connecticut. Computer Science and Engineering Department. Outline. Introduction & prior . w. ork. Our approach. Preliminary results. Conclusion and future work.