PPT-Mitochondrial genes and diseases

VBC608 Unit III PG 23112020 24112020 Mitochondrial Diseases The term mitochondrial cytopathy refers to a diverse group of inherited or acquired disorders It is heterogeneous group of disorders. 4NeoplasticProcessincludesMeSHtermsreferringtocan-cers. SemanticType IntermediateBMeSHTerms G E A Genes,jun 1 Genes,fos 2 Genes,APC 3 Genes,Reporter 4 Genes,Dominant 5 Genes,ras 6 Genes,rel 7 Genes,bc How they are caused and why they can be beneficial. What kind of genetic disease?. Can be of two kinds:. Caused by . environmental factors. Hereditary. Genetic disease by environmental factors includes cancer due to the cells undergoing . By: Dr Natasha Gerbis. Mitochondria. Mitochondria play an essential role in cellular metabolism . Convert food into energy. The “batteries” of the cell. Mitochondria. Synthesize energy molecules called ATP via oxidative phosphorylation. r. eplacement in unfertilized . o. ocytes. for . t. reatment . of . inherited . mtDNA. disease . Shoukhrat . Mitalipov. 1. Diseases caused by . mtDNA. mutations. There are more than . 700 . known disease-associated . Monogenic mitochondrial disorders. Pathologic conditions such as:. Alzheimer’s disease. Parkinson’s disease. Huntington’s disease. cancer. diabetes. obesity. epilepsy. cardiac disease. Progressive decline in the expression of mitochondrial genes is a central feature of normal human aging. in the Teaching Material of. Medical Biotechnology Master’s . Programmes. at the University of . Pécs. and at the University of Debrecen. Identification number: TÁMOP-4.1.2-08/1/A-2009-0011. Mitochondrial. . Committee on Human Gene Editing: . Scientific, Medical and Ethical Considerations . Consensus Study Meeting #2 . February 11, 2016 . Philip E. Yeske, Ph.D.. Science & Alliance Officer. United Mitochondrial Disease Foundation. Stephen Okoth BSN, SRNA (Sr.). York . College of PA/. Wellspan. Health NAP . Objectives. Discuss the structure of the Mitochondrion. Discuss . the main . function . of the . Mitochondrion. Detecting and Diagnosing mitochondrial diseases. Stephen Okoth BSN, SRNA (Sr.). York . College of PA/. Wellspan. Health NAP . Objectives. Discuss the structure of the Mitochondrion. Discuss . the main . function . of the . Mitochondrion. Detecting and Diagnosing mitochondrial diseases. CLINICAL INFORMATIONIntroductionMitochondrial disorders are a group of related, clinically diverse, genetic diseases with a prevalence of 1/5,000 to 1/8,500 that result from dysfunction of the mitocho (mitochondria and . peroxisomes. ). Dr. Mamoun Ahram. Faculty of Medicine. Second year, Second semester, 2014-2014. Principles of Genetics and Molecular Biology. What are the mitochondria?. Mitochondria are thought to have evolved from bacteria via . 10 Centre of Excellence in Alzheimer’s Disease Research and Care, School of Medical Sciences, Edith Cowan University, 270 Joondalup Drive, Joondalup, 6027, AustraliaSchool of Psychiatry and Clini 4288 European Review for Medical and Pharmacological Sciences2018; 22: 4288-4298 UOC Nutrizione Clinica, Dipartimento di Scienze Gastroenterologiche, Endocrino-Metaboliche e Nefro-Urologiche, Fondazio 4. M. . Faiyaz-Ul-Haque. , PhD, . FRCPath. Atypical Patterns of Inheritance. Lecture Objectives. By the end of this lecture, students should be able to appreciate the possibility of atypical patterns of inheritance with special emphasis on:.