PPT-Mitochondrial Disease & its Anesthetic Considerations

Stephen Okoth BSN SRNA Sr York College of PA Wellspan Health NAP Objectives Discuss the structure of the Mitochondrion Discuss the main function of the Mitochondrion Detecting and Diagnosing mitochondrial diseases. Anesthesia for a Muscle Biopsy. Case . You are assigned to do an anesthetic for a muscle biopsy. The patient is a 13 month old male toddler with delayed motor milestones. . H. e can not sit unsupported, roll over, cruise or walk yet. He was delivered at 35 weeks PCA and spent 1 week in the NICU for feeding difficulties. There were never any respiratory difficulties. Per the parents the toddler has not had any prior anesthetics. There is no family history of muscular weakness or any problems with anesthesia although mom tells you that she was adopted and knows nothing about her biological family.. By: Dr Natasha Gerbis. Mitochondria. Mitochondria play an essential role in cellular metabolism . Convert food into energy. The “batteries” of the cell. Mitochondria. Synthesize energy molecules called ATP via oxidative phosphorylation. 1 Stroke - Like Episodes in Adult Mitochondrial Disease: Investigation and Management First published November 2012 Updated Jan uary 2013 2 Contents Introduction 3 Patient - centered Care 4 Key pr . Committee on Human Gene Editing: . Scientific, Medical and Ethical Considerations . Consensus Study Meeting #2 . February 11, 2016 . Philip E. Yeske, Ph.D.. Science & Alliance Officer. United Mitochondrial Disease Foundation. Stephen Okoth BSN, SRNA (Sr.). York . College of PA/. Wellspan. Health NAP . Objectives. Discuss the structure of the Mitochondrion. Discuss . the main . function . of the . Mitochondrion. Detecting and Diagnosing mitochondrial diseases. Populatons. Pregnant. Geriatric. Diabetic. Obese . The Pregnant Patient-Physiologic Changes. The presence of fetus and placenta . Aorta and vena . caval. compression . Reflux and possible aspiration of gastric contents. Anesthesia for a Muscle Biopsy. Case . You are assigned to do an anesthetic for a muscle biopsy. The patient is a 13 month old male toddler with delayed motor milestones. . H. e can not sit unsupported, roll over, cruise or walk yet. He was delivered at 35 weeks PCA and spent 1 week in the NICU for feeding difficulties. There were never any respiratory difficulties. Per the parents the toddler has not had any prior anesthetics. There is no family history of muscular weakness or any problems with anesthesia although mom tells you that she was adopted and knows nothing about her biological family.. “ ASK THE MITO DOC ” QUESTIONS Q . Do you have any studies or information about the use of Botox in patients with mitochondrial diseases? A. I would OigOly douNP POMP POere’s Mny sucO sPudy. This is a Mitochondria, let’s call it MiTO for short,they are tiny but mighty...They are in your cells and make your body work. Especially dedicated to Tom, who is so brave,in his battle withMitocho Understanding the new Recommendations of the Safety of . Drug Use in Patients with Primary Mitochondrial Disease. Presented by: Dr. . Amel. . Karaa. Understanding the New Recommendations of the Safety of . VBC-608. Unit- III. P.G.. 23.11.2020. 24.11.2020. Mitochondrial Diseases. The term mitochondrial cytopathy refers to a diverse group of inherited or acquired disorders.. It is heterogeneous group of disorders.. Dr . Rebecca Dimond. DimondR1@Cardiff.ac.uk . @. BecDimDiff . Translation in Healthcare - Exploring the Impact of Emerging . Technologies 25. th. June 2015 . . What is Mitochondrial disease?. Cerebral . Folate. Deficiency in . Autism Spectrum Disorder. Richard E. Frye, M.D., Ph.D.. Director of Autism Research . Associate Professor of Pediatrics. Arkansas Children’s Hospital. The Rise in Autism. Dr R P Pandey. IV. Onset is and peak effect is quick, effect is intense, duration of action short. IM. Onset in 10-15 min, peak effect is delayed, depends on tissue perfusion/drug absorption/metabolism.