PPT-Clinical Cancer Genetics in

Breast and Ovarian Cancers The Role of Cancer Genetics in Precision Medicine April 17 2018 amp May 1 2018 Preeti Sudheendra MD Assistant Professor of Medicine Division of Hematology and Oncology. 1 Roles of the Clinical Geneticist This statement represents a consensus reached by the Council of the Clinical Genetics Society (CGS) in 2011 and is an updated revision of an earlier document, entitl Do A m Wo We Gwtick Wo W Sda Ha Ieict Iaca Sa Imfm Ri A m Wi We Gwtick Wo Wei Sr Ha Iibr CaiptoT Ioc Pcc Xi A m Wi Weo Gwtick W W X Icho Ih Ha Ita Itb Wctc Mc Stip X N X Y X X X Y X X C f N f A m N m 0 8 /2013 CANCER GENETICS & PREVENTION LYNCH SYNDROME (LS) PATIENT INFORMATION What is Lynch syndrome? Lynch syndrome, also known as Hereditary Non - Polyposis Colorectal Cancer (HNPCC) is the most c & Hereditary. Pancreatitis. David C Whitcomb MD PhD AGAF. . Giant Eagle Foundation Professor of Cancer Genetics.. Professor of Medicine, Cell Biology & Physiology, and Human Genetics. Chief, Division of Gastroenterology, Hepatology and Nutrition. . Next Generation Sequencing:. A technical perspective. Bristol Genetics Laboratory. Joanne Davies. Genetic Technologist. Objectives. Summarise the NGS assays currently available at BGL. Look at the general challenges with NGS assays. Refer to Clinical Genetics. Send patient details, result and . histology report to . cancergenetics.stg@nhs.net . Other . histopathological. subtypes. Adenocarcinoma. High grade serous. Refer. to clinical genetics if concerned about personal or family history only. significantly decreased likelihood of genetic cause for medullary thyroid cancer. If relevant personal or family history: send patient details via email to . cancergenetics.stg@nhs.net. for review. If further action indicated, Clinical Genetics will request a formal referral. . 14/12/2021. overview. My focus is on teaching you . concepts. you don’t get yet. We’ll be skipping rote learning content (make sure you cover them though!). Phenotypic. Variability. Genetic . Testing. 1. Patient has pancreatic cancer age <50 years, OR . 2. Patient has pancreatic cancer age <60 years, AND . a. Personal history of breast cancer age <60, melanoma age <60, OR ovarian cancer, OR . Send patient details, result and . histology report to . cancergenetics.stg@nhs.net . Eligibility in Test Directory. (R254). Patient with. possible heritable skin. cancer. Unable to establish if patient meets testing criteria. Antonius Schuh, Ph.D. | . Chief Executive Officer. September . 2013. Forward-Looking Statements. Statements in this presentation about the Company's expectations, applications of its technology, markets, launch of tests and other statements that are not historical facts are "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934 and are based on management's current beliefs, assumptions, estimates and projections. Actual results may differ materially from those projected in the forward-looking statements for various reasons, including risks associated with product and test development, test transfer to contracting labs, government regulation, market acceptance, limited commercial experience, dependence on key personnel, obtaining financing and other factors discussed in the Company's periodic reports filed with the Securities and Exchange Commission.. (. Genomic Test Directory criteria R208): . Ask. patient to complete family history screening questionnaire. Germline/somatic genetic test pathway:. Clinical team discuss testing with the patient. Complete test request forms and record of discussion form. Patient with a new diagnosis of Endometrial cancer . MCG-LYNCHEndoNUHProtocol V3March 2022. . Planned review: March 2023. Author CJS/CVL. DIAGNOSIS OF LYNCH SYNDROME UNLIKELY. Refer to clinical genetics if:. Patient meets eligibility criteria as per . National Genomic Test Directory. . Take family history, consider drawing a family pedigree . Discuss gene testing and 3 possible results. Give information sheet to patient.