PPT-http://www.nbt.nhs.uk/genetics

Next Generation Sequencing A technical perspective Bristol Genetics Laboratory Joanne Davies Genetic Technologist Objectives Summarise the NGS assays currently available at BGL Look at the general challenges with NGS assays. http://www.dnapolicy.org/. “A . treatable . disease . like . severe asthma”. “Having a bad . reaction to . certain types of medicine”. No. Yes. “An . untreatable . disease . like . Alzheimer’s”. Stephen Montgomery. smontgom@stanford.edu. montgomerylab.stanford.edu. @. sbmontgom. Identifying the genes and variants responsible for disease.. Monogenic to polygenic diseases. Rare to common variants. Traits. - Characteristic, quality, or feature that distinguishes an organism. Genetics. /Heredity. - . The passing on of traits from parent to offspring. Acquired Trait. - Trait that is learned or obtained through experience or practice.. A. Structure of DNA. 1. discovered by James Watson and Francis Crick in 1953. 2. stores genetic information for the production of proteins. 3. composed of nucleotides. A) a nucleotide is composed of a nitrogenous base, sugar, and phosphate. Next Generation Technology . Developments and Applications:. Now and Potential across Healthcare. Eileen Roberts. Thalia Antoniadi. http://www.nbt.nhs.uk/genetics. The changing landscape . Advances in technology are altering the landscape of medical care . Next Generation Sequencing:. A technical perspective. Bristol Genetics Laboratory. Joanne Davies. Genetic Technologist. Objectives. Summarise the NGS assays currently available at BGL. Look at the general challenges with NGS assays. Overview Position – NHS 111 across South Central. SCAS Responsibilities . Risks and Challenges faced . Activity, Outcomes and Performance in Berkshire . Questions . I will cover. NHS 111 Service Provision – South Central Region. Objective . Tonight’s Homework. To see how genotype and phenotype apply. pp 127: 2, 5. Finish the “odds” for your kid. Making a Kid Using Genetics. In this activity, you’ll be pairing up with a friend and combining traits to make a kid. One of you will be “mom” and the other will be “dad”. Choose however you want.. Two organisms. One characteristic. Complete dominance . Solving Genetics Problems : Monohybrid Crosses. Complete dominance . the . dominant allele. completely masks the effect of the . recessive allele. STANDARD. - . 5.NBT.3, 5.NBT.7. . . Objective:. . D. ivide decimals by single-digit whole numbers 
involving easily identifiable multiples using place 
value understanding and relate to a written 
method.. Knowing your NHS Starter Ideas The NHS in numbers How many people does the NHS treat every 24 hours? Approximately, how many GP appointments are there in a a year? Approximately, how many A&E attendances are there in a year? 1 PIGO gene phosphatidylinositol glycan anchor biosynthesis class O Normal Function The PIGO gene provides instructions for making one part of an enzyme called GPI GPI-ET3GPI-ET3 produced from a ge 2015 - 2016. Tanya donated 416 horseshoes to the Helpful Horse Foundation. Rounded to the nearest hundred, how many horseshoes did she donate?. a.. b.. c.. d.. 500. 420. 410. 400. 4.NBT.3. a.. b.. c.. 1. . Discovered . by James Watson and Francis Crick . in 1953. 2. . Stores . genetic information for the production of proteins. 3. . Composed . of nucleotides. A) . A . nucleotide is composed of a nitrogenous base, .