PPT-Combined sequence based and genetic mapping analysis of complex traits in outbred rats

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Baud A et al Rat Genome Sequencing and Mapping Consortium Presented by Alex Gileta Hailing from the Palmer Lab Nature Genetics 45 767775 2013 Genetic Variation

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Combined sequence based and genetic mapping analysis of complex traits in outbred rats: Transcript

Baud A et al Rat Genome Sequencing and Mapping Consortium Presented by Alex Gileta Hailing from the Palmer Lab Nature Genetics 45 767775 2013 Genetic Variation and Complex Traits. Baud, A. et al. . Rat Genome Sequencing and Mapping Consortium. Presented by Alex . Gileta. Hailing from the Palmer Lab. Nature Genetics . . 45. , . . 767–775 (2013). Genetic Variation and Complex Traits. Genome sequencing. Next Gen sequencing. Genomics = resources. genome maps. genome sequences. genome clones. DNA microarrays. whole gene collections. functional genomics!. 1980- 1998. 1977- 2003. DNA mapping. Daniel M. Gatti, . Ph.D. Berlin, Germany. May 2014. Outline. Introduction. Genotyping Diversity Outbred Mice. Quantitative Trait Locus mapping in DO mice. Motivation for producing the DO. Known founders to perform linkage mapping. Introduction. How genetic selection works. Gains due to genetic selection. Use of genomic technology. Future research opportunities. How does genetic selection work?. ΔG = . genetic gain each year. reliability =. Kernel Composition in the . Nested Association Mapping (NAM) Population. Sherry Flint-Garcia. USDA-ARS Columbia, MO. Outline. Development of NAM Population. Kernel Composition. Joint Linkage Mapping. Kernel Composition in the . Nested Association Mapping (NAM) Population. Sherry Flint-Garcia. USDA-ARS Columbia, MO. Outline. Development of NAM Population. Kernel Composition. Joint Linkage Mapping. petercelec@gmail.com. www.imbm.sk. Linus. . Carl. . Pauling. (1901 – 1994). Nobel. . prize. 1954 – . Chemistry. 1962 – Peace. Francis. . Crick. (1916 – 2004). Nobel. . p. rize. 1962 – . 15, 2021. dsenol@andrew.cmu.edu. . Committee: . Prof. Onur Mutlu (CMU, ETH Zurich). Prof. Saugata Ghose (CMU, UIUC). Prof. James C. Hoe (CMU). Prof. Can Alkan (Bilkent University). ore . A. ccurate. Truong SK, McCormick RF, . Morishige. DT, Mullet JE (2014) Resolution of genetic map expansion caused by excess heterozygosity in plant recombinant inbred populations. G3 (Bethesda) 4: 1963-1969. 1 Genetic and Physical MappingThe ultimate goal of mapping is to identify the gene(s) responsible for a given phenotype or the mutation responsible for a specific variant.The initial steps in mapping cation of marker-trait associations, mapping Quantitative Trait Loci (QTL), candidate gene identi cation, basis for high-resolution genetic ne-mapping, which provide powerful tools for genetic anal ___________________________________________________________________________Available online at www.jocpr.com Genetic Markers - A Cutting-Edge Technology in Herbal Drug Research The Human Genome Project THE ISRAEL ACADEMY OF SCIENCES AND HUMANITIES FOREWORD The concept of deciphering the Human Genome surfaced in the United States in the 1930s following the discoveries th Clement Ma. Sequence Analysis Workshop. May 21, 2015. Lecture slides adapted from Hyun Min Kang and . Gonçalo. . Abecasis. Outline. Introduction. Data overview. Analysis of common variants. Analysis of low-frequency variants.

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