PPT-QTL Mapping in Diversity Outbred Mice

Daniel M Gatti PhD Berlin Germany May 2014 Outline Introduction Genotyping Diversity Outbred Mice Quantitative Trait Locus mapping in DO mice Motivation for producing the DO Known founders to perform linkage mapping. Nisha Crouser and James Stewart. Building strong bones and teeth. Clotting blood. Sending and receiving nerve signals. Squeezing and relaxing muscles. Releasing hormones and other chemicals. Keeping a normal heartbeat. Chapter 6. Once again, the scene opens on the clearing in the woods, with the riverbed and its surroundings described as beautiful and idyllic toward the end of a day. . Many details are repeated from the book’s opening passages, such as the quality of the sunlight, the distant mountains, and the water snakes with their heads like “periscopes.” . Baud, A. et al. . Rat Genome Sequencing and Mapping Consortium. Presented by Alex . Gileta. Hailing from the Palmer Lab. Nature Genetics .  . 45. , . . 767–775 (2013). Genetic Variation and Complex Traits. RFCC Module Status: RF Cavities. Derun. . Li. A. . DeMello. , S. . Virostek. , M. . Zisman. Lawrence Berkeley National . Laboratory. NFMCC . Collaboration Meeting. The University of Mississippi, Oxford, MS. K Ronald, University of Strathclyde. For the MICE RF team. 1. MICE Project Board 14th November 2013. Specifications for the MICE RF system. To demonstrate sustained cooling (MICE Step VI) requires 8 cavities at 8MV/m. Kulikov . A.V.. Federal Research Center Institute of Cytology and Genetics, Siberian Division of Russian Academy of Sciences, 630090, Novosibirsk, Russia. Catalepsy. Experimental models of catalepsy. resequencing . of circa 1,000 lines was accomplished, including world reference genotype Tift . 23D. 2. B. 1. P1-P5. , association mapping panel (PMiGAP), wild species from West and Central Africa (WCA) and hybrid parental lines from SAUs and . Dr Kat Gupta. Oxford Brookes University, UK. @. mixosaurus. Outline. Images of diversity. Rethinking diversity. What could/should a diverse organisations look like?. Images of diversity. "Diversity is something that's being marketed [...] They're trying to sell a campus climate, they're trying to sell a future. Campuses are trying to say, 'If you come here, you'll have a good time, and you'll fit in.' ". Zenglu Li. Department of Crop and Soil . Sciences. / Center for Applied Genetic Technologies. March 9, 2015. Acknowledgements. Postdoc Scientists and Graduate Students. Donna . Harris. Justin Vaughn . Kernel Composition in the . Nested Association Mapping (NAM) Population. Sherry Flint-Garcia. USDA-ARS Columbia, MO. Outline. Development of NAM Population. Kernel Composition. Joint Linkage Mapping. {in the classical twin design}. Slide acknowledgements (fonts all over the place and inconsistent color coding): . Manuel . Ferreira. , . Pak Sham. , . Shaun Purcell. , . Sarah Medland. , . and . Sophie . these tools may offer educators as yet unrealised and potentially complementary functions to aid The over-riding aim of all mapping tools is similar. If students can represent or manipulate a complex Baud, A. et al. . Rat Genome Sequencing and Mapping Consortium. Presented by Alex . Gileta. Hailing from the Palmer Lab. Nature Genetics .  . 45. , . . 767–775 (2013). Genetic Variation and Complex Traits. Dr.. Danny Arends. Northumbria University, Sept 2022. danny.arends@northumbria.ac.uk. About me. QTL mapping in 3 slides. LMM-MQM time series mapping. Linear mixed models & Multiple QTL mapping. More statistical power through modelling of time series .