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The Nurse View:  Hormone Receptor-Positive Advanced Breast Cancer The Nurse View:  Hormone Receptor-Positive Advanced Breast Cancer

The Nurse View: Hormone Receptor-Positive Advanced Breast Cancer - PowerPoint Presentation

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Uploaded On 2018-10-30

The Nurse View: Hormone Receptor-Positive Advanced Breast Cancer - PPT Presentation

HR Advanced Breast Cancer Introduction Restaging at Relapse vs De Novo Metastatic Disease Visceral Crisis Personalizing Endocrine Therapy Endocrine Therapy Landscape FIRST Trial Fulvestrant vs Anastrozole ID: 703708

advanced letrozole breast paloma letrozole advanced paloma breast endocrine therapy cancer safety patients trial anastrozole exemestane everolimus adherence fulvestrant

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Presentation Transcript

Slide1

The Nurse View: Hormone Receptor-Positive Advanced Breast CancerSlide2
Slide3

HR+ Advanced Breast CancerIntroductionSlide4

Restaging at Relapse vs De Novo Metastatic DiseaseSlide5

Visceral CrisisSlide6

Personalizing Endocrine TherapySlide7

Endocrine Therapy LandscapeSlide8

FIRST TrialFulvestrant vs AnastrozoleSlide9

FIRST Trial -- SafetySlide10

FALCON: Anastrozole vs Fulvestrant in HR+ Advanced or Metastatic Breast Cancer Slide11

FALCONMost Common AEs (> 5%)Slide12

Aromatase InhibitorsManagement of AEsSlide13

HOPE StudyExercise AdherenceSlide14

Overcoming Endocrine Resistance in MBCSlide15

PALOMA-2 Palbociclib + Letrozole vs Letrozole Alone Slide16

PALOMA-2AE SummarySlide17

Palbociclib Dosing and Drug InteractionSlide18

PalbociclibManagement of Hematological ToxicitiesSlide19

MONALEESA-2: Ribociclib + Letrozole vs Letrozole in HR+ Advanced Breast Cancer Slide20

MONALEESA-2Safety ProfileSlide21

Managing Treatment-Related Adverse Events from CDK InhibitorsSlide22

BOLERO-2 Everolimus + Exemestane vs Placebo + Exemestane Slide23

BOLERO-2Most Common Grade 3/4 Adverse EventsSlide24

SWISH Trial Dexamethasone-Based Mouthwash for StomatitisSlide25

Management Issues With EverolimusSlide26

PALOMA-3Palbociclib + Fulvestrant in Pre/Perimenopausal M

BCSlide27

PALOMA-3 Safety ResultsSlide28

Educating our patientsSlide29

Managing Adherence to Oral TherapySlide30

Specific Measures To Manage PatientsSlide31

Concluding RemarksSlide32

AbbreviationsSlide33

Abbreviations (cont)