Why am I taking virology? - PowerPoint Presentation

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Why am I taking virology?Dr. James Maruniak

1. You have viruses.

2. You will give someone your virus.

3. Someone could die including you from your virus.

4. These viruses could interfere with your quality of life, your sex life, and reproductive capability.

5. You can do something about them.

6. You will use your knowledge in your professional career. Slide2

*Slide3

http://entnem.ifas.ufl.edu/maruniak/virologySlide4

http://www.cals.ufl.edu/honors/Slide5

MCB 4503 GENERAL VIROLOGY

Instructors:

This course is taught by Drs. James E. Maruniak with the following guest lecturers:

Polston

,

Small and Yamamoto. The lectures are Monday, Wednesday and Friday, 8:30 a.m. to 9:20 a.m.General description: This course is for undergraduate students in microbiology and related disciplines. The course teaches basic information on families of viruses from humans, plants, insects, animals and bacteria. Lectures cover the basic information of the medical, clinical, diagnostic, biotechnological, and molecular aspects of these viruses.

Prerequisites:

Any basic course in microbiology, genetics, biochemistry or molecular biology.

Gatorlink

Account

"All UF students are required to have an active

Gatorlink

account. You may obtain a

Gatorlink

account by logging on to

http://www.gatorlink.ufl.edu

, or by visiting the Circa lab located across from

Turlington

Hall and signing up.

Textbook:

No

textbooks are required for the virology course. The textbook at the library is

Jawetz

et al. Medical Microbiology, 26th Edition, ISBN 978-0-07179-031-4 (eBook* available through UF libraries: http://uf.catalog.fcla.edu/uf.jsp?st=UF031735546&ix=pm&I=0&V=D&pm=1

*Please note that you MUST be logged on to UF library website or

Gatorlink

VPN to access this eBook off-campus)

The course will use the internet to search for current information to answer questions during and after class period. Come prepared with your laptop computer and to interact with other students.

Course

grade:

The course grade will be determined by four exams, each counting 50 points. There are no regular make-up exams. If you miss an exam, one test score can be dropped; however, you can take a comprehensive makeup for one test at the end of the course during the regularly scheduled final exam. The last of four exams will be given on

Apr. 16.

If

you miss the fourth test with an acceptable medical or family excuse, you can take a make-up test during the scheduled final exam.

All students must take the fourth or final exam with a passing grade or receive an incomplete grade.

The tests questions are multiple choice with one or more answers, fill-in blanks and drawings. Information for tests will be from

lectures

and handouts.

Letter grades are based on the percent of 150 total points: A=100-90%, B+=89.9-88%, B=87.9-80%, C+=79.9-78%, C=77.9-70%, D=69.9-60% and below 60%=E.Slide6

MCB 5505 GENERAL VIROLOGY

Instructors:

This course is taught by Drs. James E. Maruniak with the following guest lecturers:

Polston

, Small and Yamamoto. The lectures are Monday, Wednesday and Friday, 8:30 a.m. to 9:20 a.m.General description: This course is for beginning graduate and honor students in microbiology and related disciplines. The course teaches basic information on families of viruses from humans, plants, insects, animals and bacteria. Lectures cover the basic information of the medical, clinical, diagnostic, biotechnological, and molecular aspects of these viruses.

Prerequisites:

Any basic course in microbiology, genetics, biochemistry or molecular biology.

Gatorlink

Account

"All UF students are required to have an active

Gatorlink

account. You may obtain a

Gatorlink

account by logging on to

http://www.gatorlink.ufl.edu

, or by visiting the Circa lab located across from

Turlington

Hall and signing up.

Textbook

:

No textbooks are required for the virology course. The course will use the internet to search for current information to answer questions during and after class period. Come prepared with your laptop computer and to interact with other students.

Course grade:

The course grade will be determined by four exams, each counting 50 points. There are no regular make-up exams. If you miss an exam, one test score can be dropped; however, you can take a comprehensive makeup for one test at the end of the course during the regularly scheduled final exam. The last of four exams will be given on April

16, 2014.

If you miss the fourth test with an acceptable medical or family excuse, you can take a make-up test during the scheduled final exam.

All students must take the fourth or final exam with a passing grade or receive an incomplete grade.

The test questions are multiple choice with one or more answers. Information for tests will be from lectures, handouts and the course CD.

Graduate students are expected to write a portfolio on 5 virus families in a specialty area for their future career and give a 10-12 minute oral presentation in class as a panel discussion (50 points). Letter grades are based on the percent of 200 total points: A=100-90%, B+=89.9-88%, B=87.9-80%, C+=79.9-78%, C=77.9-70%, D=69.9-60% and below 60%=E.Slide7
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Software Use:

All faculty, staff and students of the University are required and expected to obey the laws and legal agreements governing software use. Failure to do so can lead to monetary damages and/or criminal penalties for the individual violator. Because such violations are also against University of Florida policies and rules, disciplinary action will also be taken as appropriate.

Email:

I read email, but because of the volume of University email to me, I do not always get back right away. All University of Florida students are required to have a Gatorlink account that I can use to email you for special announcements.Slide9

MCB 4503

Virology

ClassroomSlide10

NUMBER OF

STUDENTS

CORRECT ANSWERS OF 50 QUESTIONS

ON A VIROLOGY EXAMSlide11

Hey Dr. Maruniak, this is Tim Miller. I took your class this past spring, 2005.

I don't do this with many of my professors... well actually, I never have, but now that I don't have you as a professor anymore, and therefore could not be doing this for "brownie points," I just wanted to let you know how much I enjoyed your class. I usually dread sitting through college classes, especially at 8 in the morning, but I really enjoyed learning in your class. Also, the slides on DVD is really a great learning tool...

I found that when I was taking your tests, I could actually hear your voice in my head going over the information that was being asked about. I don't remember half of the stuff that I've learned in other classes, but I really remember almost everything from Virology.

I ended up with what I consider an easy A, but not because the class or tests were easy, but rather because you presented the information in such a way that it became easy for me. Anyway, I'm in the process of applying to medical schools and doing well with everything. I'm going to be going to Honduras right after Christmas to do some missionary work: helping to finish building an orphanage, and subsequently moving in many orphaned children and caring for them... Then its off to med school.

I hope all is going well with you and your family. I just wanted to let you know how much I appreciate what you have done for me. I don't think you realize how much you affect your students, but your really have affected my in such a positive way, and I will never forget it, or you. Thank you.

Sincerely,

Timothy D. Miller Jr.Slide12
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Carrie

Mewha

UF Microbiology & Cell Science graduate

She is from St. Petersburg, Florida, and was the valedictorian of St. Petersburg High School.

Mewha

was a National Merit Scholar and graduated from the University of Florida with bachelor degrees in microbiology and cell science. Later she went on the Medical School at the University of Miami, and specialized in maternal-fetal medicine.Carrie Ann

Mantha

 (née

Mewha

) was the Miss Florida USA for 2003, is a licensed Medical Doctor, and now works as an analyst covering biotechnology stocks for Galleon, a New York hedge fund.Slide14
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http://www.cdc.gov/flu/weekly/downloadimage.htm?w=53Slide16
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December 15th, 2012 12:28 PM ET

Hillary Clinton faints, suffers concussion

U.S. Secretary of State Hillary Clinton sustained a concussion after becoming dehydrated and fainting, a State Department official said.

Clinton had been

suffering from a stomach virus at the time

, according to a statement on Saturday from Philippe Reines, deputy assistant secretary of state.She is being monitored by doctors and is recovering at home. She was never hospitalized, Reines said.Slide20

Virus Seen in Muscle from Chronic Fatigue Patients

Mass. Woman Sues Over HIV Misdiagnosis

Fewer Women to Need Annual Cervical Tests

Researchers: Pill Stops Spread of Herpes

Flu Deaths Hit Epidemic Level in U.S.

The Offal Truth: People Enjoy Eating Calf BrainsArk. Officials Limit Sharing Information About Flu Deaths, Citing New U.S. Medical Privacy Law

Japan Patient Receives HIV-Tainted Blood

Flu Outbreak Strains Demand for Test Kits

South Korean Bird Flu Outbreak Spreads

Expert warns MMR scare could spark measles epidemic in Britain

Flu Shot Unable to Combat Virus Strain

Four Children in Colorado Die From Flu

Green Onions Suspected in Hepatitis Cases

Human Papillomavirus Tied to Oral Cancer

Italy Launches New AIDS Vaccine Trials Based on Tat

New Australian research links breast cancer to a virus

Rules to Stop Monkeypox Spread in U.S. Finalized

Vaccine-Evading Mousepox Virus Created

Churches Say Condoms Don't Stop AIDS

Gene Therapy Did Cause Cancer in Boys

Smallpox Vaccine Could Prevent AIDSSlide21

Danny Wuerffel continues recovery from Guillain-Barre syndrome

December 07, 2011|By Rachel George, Orlando Sentinel

GAINESVILLE — Former Florida QB

Danny Wuerffel

continues his recovery from Guillain-Barre syndrome but writes in his latest update that "life is tough."

Wuerffel has been dealing with Guillain-Barre, which causes the immune system to attack the nerves in response to an infectious illness, since being hospitalized in June. He has posted periodic updates on the website for Desire Street Ministries, where he is the executive director."I've been battling with GBS for over six months now, and the difficulties in my life related to the illness continue to make life much harder than I want," Wuerffel wrote. "Overall, I'm doing better and I'm thankful for the progress."A Thanksgiving trip to visit in-laws left him drained, and Wuerffel writes that some days he doesn't have the energy to complete a few simple tasks. Life has seasons, Wuerffel writes, and right now he feels like he's in the winter.

Wuerffel was diagnosed not long after the unveiling of a statue of him at the UF spring game. The University Athletic Association unveiled bronze statues of Wuerffel and Florida's other Heisman Trophy-winning QBs —

Tim

Tebow

and

Steve

Spurrier

— at that game in April.Slide22

Stricken cruise ship docks for cleaning

By JENNIFER KAY, Associated Press Writer

A thorough scrubbing of the Carnival Liberty began Sunday as the ship docked after a virus sickened nearly 700 passengers on a trans-Atlantic cruise.

Fourteen guests and five crew remained ill and in isolation when the ship arrived at Port Everglades, according to a statement released by Carnival Cruise Lines, a brand of Carnival Corp. Some passengers were escorted off the ship in wheelchairs by crew wearing blue gloves.

Preliminary tests identified the source of the outbreak as the highly contagious norovirus, which had struck several guests just before they boarded the cruise Nov. 3 in Rome, Carnival officials said. More than 530 guests and 140 crew reported to the ship's infirmary with similar symptoms during the 16-day voyage.Slide23

Thousands of Britons sickened by virus

Thousands of people in Britain have been sickened by the biggest outbreak of a winter vomiting virus in five years. Doctors estimate that hundreds of thousands of people may be affected by norovirus in the coming days. Dozens of hospital wards across the country have already been closed to try to stop the virus' spread.

"General practitioners are seeing a huge number of cases of patients with the norovirus," said Steve Field, chairman of the Royal College of General Practitioners.

Norovirus is the most common stomach bug in the United Kingdom, and its incidence typically spikes during the winter.

"The norovirus season has started uncharacteristically early compared to other years," said the Health Protection Agency in a statement. Most cases go unreported, and the agency estimates that for every case, there are 1,500 others.

Symptoms include nausea, projectile vomiting, diarrhea, fever and muscle pain. Most people recover within two days without treatment, though the virus can be more serious in the very young or the elderly.

The Health Protection Agency estimates that there are between 600,000 and 1 million cases of norovirus in the U.K. every year. Numbers of cases vary every year, and the agency said that this year's figures are not yet exceptional.Slide24

Virus leads to Federer withdrawal

World number one Roger Federer has withdrawn from the Kooyong Classic in Melbourne because of a stomach virus.

The eight-man exhibition tournament is a warm-up for the Australian Open which begins on 14 January, with Federer hoping to retain his title.

"After arriving in Australia I came down with a stomach virus and it continued to get worse," said Federer. Slide25

Polo returns to Boca Raton area without worries about equine virus

Match opens season free of last year's worries about equine virus

By

Chrystian

Tejedor | South Florida Sun-Sentinel January 7, 2008 West Boca - Horse hoofs kicked up patches of dark green sod Sunday. Men with mallets whacked a tiny white ball up and down the field, and Tom Oxley's voice blared over loudspeakers.

Polo season has returned to the Royal Palm Polo Club west of Boca Raton.

"I look forward to this from now to the middle of April," said longtime spectator John Hinckley, of Boca Raton. "Once you're here, you know why people come."

Sunday's John T. Oxley Memorial, played in honor of the Royal Palm Polo Club's builder and Tom Oxley's father, marks the beginning of the January-to-April polo season.

Before the start of the 2007 season, equestrians in Palm Beach County were fretting over

an equine herpes virus outbreak in Wellington that killed at least six horses

and infected seven others across the state. The village and the Royal Palm Polo Club went under a voluntary quarantine that ended just as the season was to begin.Slide26

Lauren

Fant

, left, 18, winces as she has her third and final application of the

HPV vaccine administered by nurse Stephanie Pearson at a doctor's office

,

in Marietta, Ga. This groundbreaking vaccine that prevents

cervical cancer

in

girls is gaining a reputation as the most painful

of

childhood shots, health experts say.Slide27

Glaxo Vaccine Stops Virus Linked to Cancer

LONDON (Reuters) -

It's one of the most common cancers in women and kills about a quarter of a million patients each year but scientists said on Friday that a new vaccine could prevent most cases of cervical cancer.

The researchers tested a vaccine that protects women against two strains of the human papillomavirus (HPV) which are linked to more than 70 percent of cervical cancer cases. The vaccine was developed by drugs giant GlaxoSmithKline Plc. Slide28

Study Reveals Why Flu Thrives in Winter

Oct 18, 2007

For the first time, scientist have solid evidence suggesting exactly why the flu is so common in winter.

A new animal study suggests that the influenza virus' success hinges on low relative humidity and cold temperatures. Such conditions keep the virus more stable and in the air longer than warm, humid conditions, scientists said. And apparently, the frosty weather's role is more important than that of the human body in helping the virus thrive.

"We've always thought the immune system wasn't as active during the winter, but that doesn't really seem to be the case," said study coauthor Peter Palese, a virologist at the Mount Sinai School of Medicine in New York City.

When we cough or sneeze, tiny droplets of water enter the air and hang around until they drop to the ground—or an unsuspecting passerby breathes them in. Once inside our airways, any flu viruses that have hitched a ride on the droplets can launch an attack.

"We found that the flu's transmission period is much, much longer when temperatures and humidity levels are low," Palese told LiveScience. Slide29

Henson Returns To Aggies Bench

He'll Coach From A Wheelchair

Monday, January 03, 2005

--

The "Lou Do" is back.

Lou Henson will return to the Aggies bench on Saturday to coach New Mexico St. against North Texas in the Sun Belt Conference opener.

Henson, 22 victories short of becoming only the fifth Division I basketball coach with 800, was

stricken with viral encephalitis

three months ago. The disease - an acute inflammation of the brain- caused paralysis in Henson's right leg.

He'll eventually fully recover but for this season Henson will coach from a wheelchair. Slide30

N.H. warns dozens at risk of meningitis

January 4, 2007

More than 80 people in three states may be at risk for meningitis after coming into contact with a University of New Hampshire student who died of the illness this week, health officials said.

The college student, 21-year-old Danielle Thompson, had been in her home state of Maine, as well as in Massachusetts and New Hampshire, in the 10 days before she was admitted to a Dover hospital. She died of bacterial meningitis on Wednesday.

Health and Human Services Commissioner John Stephen said the state has identified 29 people in New Hampshire and 55 in Maine who should receive antibiotics. Officials were still tracking down how many people Thompson visited in Massachusetts.No one has yet shown symptoms, Stephen said.

Bacterial meningitis can be spread through saliva, creating the most risk for people who shared food or drinks, kissed or used the same eating utensils. It causes an infection of fluid in the spinal cord and surrounding the brain, with symptoms include high fever, headache and stiff neck.

"This case underscores just how serious this illness can be," Stephen said.

In Rhode Island, epidemiologists from the U.S. Centers for Disease Control and Prevention are working with state

officials investigating a possible case of meningitis and three cases of encephalitis

that surfaced in public school children. One

second-grader in Warwick died from encephalitis that was brought on by "walking pneumonia.“

Signs and symptoms of walking pneumonia usually include a severe cough, fever, abdominal pain, headaches, and chills.

Mycoplasma pneumoniae

, the organism that causes walking pneumonia, can be contagious if contact with the infected person is prolonged. Walking pneumonia is transmitted through airborne droplets, which are dispersed when a person talks, sneezes, coughs or laughs.

Slide31

Condoms urged in prisons to curb AIDS in blacks

By Will Dunham Thu Nov 16, 2007

U.S. prisons should make condoms available to inmates and test for HIV as part of a broader effort to curb the spread of AIDS among blacks, hit disproportionately hard by the incurable disease, experts urged on Thursday.

The National Minority AIDS Council advocacy group, backed by U.S. black lawmakers and medical leaders, issued a series of recommendations aimed at U.S. policymakers to slow the epidemic among blacks, 10 times more likely than whites to have AIDS.

"In 2006, AIDS in America is a black disease," said

Phill

Wilson, executive director of the Black AIDS Institute in Los Angeles.

With U.S. black men seven times more likely than whites and three times more likely than Latinos to be imprisoned, the council's report said

incarceration has become "one of the most important drivers of HIV infection among African-Americans

."

More than half of new U.S. HIV infections are in blacks, according to the Centers for Disease Control and Prevention.Slide32

Serial HIV Assault Verdict Expected

OLYMPIA, Wash. - November 5,

2004

A verdict will be announced Monday in the trial of a man charged with intentionally exposing 17 women to HIV, a county judge said.

"Sex machine," "Russian roulette" and "sex addiction" were among the phrases lawyers used Thursday in 2 1/2 hours of closing arguments in the case of Anthony E. Whitfield, 32, of Lacey.

Whitfield, formerly of Oklahoma City, is charged with 17 counts of first-degree assault with sexual motivation, witness tampering and violating a court protection order. He could be sentenced to 137 to 182 years in prison if convicted on all counts.

Five of the women cited in the case have been infected with the virus that causes AIDS. Slide33
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Common Virus Ups Risk of Problems in Heart Patients

NEW YORK (Reuters) - Tue, Dec 24, 2002

People with heart disease appear to be at a slightly increased risk of life-threatening cardiovascular problems if they are infected with a common virus belonging to the herpesvirus family, according to new research.

Among more than 3,000 people with heart disease, those whose blood carried antibodies--a sign of current or past infection--to cytomegalovirus (CMV) showed a 24% increased risk of experiencing a heart attack or stroke, or of dying from cardiovascular disease within 4-1/2 years.Slide35

DRUG WATCH 3-18-2002:

CIDOFOVIR

Gilead Sciences of Foster City, CA, has developed the antiviral drug cidofovir as an intravenous injectable liquid (Vistide) for treating cytomegalovirus (CMV) retinitis, a sight-threatening infection of the inner eye, and as a topical gel (Forvade) for treating herpes simplex blisters and sores that do not respond to standard acyclovir (Zovirax) treatment.

The gel has also been studied for treating genital warts caused by human papillomavirus infection, for molluscum contagiosum and for Kaposi’s sarcoma lesions.Slide36

Herpes Infections Common Among Lesbians

Nearly half the women (46 percent) who participated in the study were positive for HSV-1, which is the usual cause of "cold sores," the report indicates, and 7.9 percent were positive for HSV-2, which causes genital infections.

The study is the first to report on HSV prevalence in this group specifically, Dr. Jeanne M. Marrazzo from Harborview Medical Center, Seattle, Washington told Reuters Health.

Marrazzo and colleagues obtained medical and sexual histories from 392 women (including both members of 71 couples) who reported sex with another woman within the preceding year, and tested their blood for HSV-1 and HSV-2 antibodies.

Most of the women (80 percent) reported having had sex with a man at some time, and 28 percent had sex with a man in the previous year. Among 257 women who self-identified as lesbian, the corresponding figures were 73 percent and 8.6 percent.

"This means that routine acquisition of chronic viral sexually transmitted diseases, like herpes, human papillomavirus (HPV), HIV, and hepatitis B, can occur at the same rate as in strictly heterosexual women," Marrazzo said.

She says health care providers should keep this in mind. "Providers should really assume nothing when a woman says 'I'm a lesbian' -- at least in terms of prior viral sexually transmitted disease acquisition -- until a more complete sexual history is taken."

Jan. 2, 2004

SOURCE: Sexually Transmitted Diseases, December 2003. Slide37

Metro State University sophomore Brock Lewis from Denver, receives the FluMist flu vaccination from medical assistant Nicole Ortiz at the Auraria Student Health Center in Denver.

Brenda Gonzales, who is 7 months pregnant, receives a flu shot at the Maple Clinic in Dallas. Health officials are monitoring a surge of flu cases involving pregnant women, some of whom were so sick they had to be hospitalized. The increase is calling attention to yet another group at serious risk of the flu. The local upswing has been concentrated at Parkland Health and Hospital System in Dallas, where 80 pregnant women have been diagnosed with the flu since early October. Slide38

Sun 7 Jan 2007

Parents block plans to vaccinate nine-year-olds against sex virus

BRIAN BRADY WESTMINSTER EDITOR

WORRIED parents have blocked government plans to vaccinate girls as young as nine against a sexually-transmitted virus that can cause cervical cancer, Scotland on Sunday can reveal.

Health chiefs have abandoned proposals to offer the jab against human papilloma virus (HPV) to primary school children after parents complained that it was inappropriate for girls of such a young age.

Scotland on Sunday revealed last summer that ministers were considering offering the jab to children in a desperate attempt to stop the "epidemic" in cervical cancer. The proposals for a nationwide scheme followed successful trials of a new vaccine in Glasgow. But ministers have now been forced to concentrate on plans for the treatment on girls of at least 12 - itself a hugely controversial move.

In September, the European Commission licensed the first HPV vaccine, Gardasil, for use by females aged between nine and 26.

But campaigners protested that immunising young girls from HPV, which can cause genital warts and is blamed for up to 70% of cases of cervical cancer, could encourage them to start having sex earlier.

The government U-turn came after medical experts who make the final recommendations on the baseline defences against HPV were warned of parents' opposition. The experts also threw out proposals to vaccinate boys against HPV, despite evidence that they can transmit the virus through sexual contact.