A CTI partnership represents a signicant opportunity for leading academic investigators and institutions to enable the fast efcient translation of innovative science into clinical candidates and e PDF document - DocSlides

A CTI partnership represents a signicant opportunity for leading academic investigators and institutions to enable the fast efcient translation of innovative science into clinical candidates and e PDF document - DocSlides

2014-12-07 203K 203 0 0

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The CTI is Q QZ ZZ Z Q Q QQZQ Z Z Q Q QQ Z We believe that the combination of the operating model 64257nancial resources and scienti64257c expertise within the CTI will bring novel programs to the clinic to bene64257t investigators their ins ID: 21614

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Presentations text content in A CTI partnership represents a signicant opportunity for leading academic investigators and institutions to enable the fast efcient translation of innovative science into clinical candidates and e


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"85 A CTI partnership represents a significant opportunity for leading academic investigators and institutions to enable the fast, efficient translation of innovative science into clinical candidates and, eventually, approved therapeutics. The CTI is: " Q QZ  " ZZ Z [Q  Q " QQZQ Z Z [[Q "  Q  QQ Z We believe that the combination of the operating model, financial resources, and scientific expertise within the CTI will bring novel programs to the clinic to benefit investigators, their institutions, and most importantly, patients.
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‰Q The Centers for Therapeutic Innovation (CTI), a newly created, entrepreneurial research unit at Pfizer, Inc., is dedicated to the establishment of global partnerships between Academic Medical Centers (AMCs) and Pfizer to transform research and development through a focus on translational medicine. %ZZ QZQ Z*QZZ  ZQZ ZQ5QQZ QQQQQZZQ $5*5$5*Q QQ Q  Q 5$5*Q QQ[Z Q5$5*Z[QZQ "$Q"$QQ * Z[QZ Q Z QQZ  QQ 5QZ Q[Q QQZ ZQ Z  5$5*ZZ  Q "$[5ZQ  Q ZZ Q
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5$5*7  4Z There is one simple goal for every project funded by the CTI: Enable a principal investigator to test a novel mechanistic and/or therapeutic hypothesis that addresses unmet medical needs in human subjects. 8QQQQQ QQZ  5$5*Q* QQQ QQ  [QQQQ  ZQ    * [QQ Q  ZQ Human Antibodies Humanized Antibodies CovX Bodies ADCs Fc Fusion Proteins Therapeutic Proteins Biseptic Abs Peptides Focus on Translational Medicine "Q5Q  Q Q"$ [#Z in vitro Z  Q Z $5*QQQ  Focus on Proof-of-Mechanism "$5*QQZQ 5 Q QQ*[QQ QZ  ZQZ QQ Open Innovation 5$5*Q"[ * "$[Z Q5  Q 
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Q$5*8 Organization CTI Laboratories at Academic Medical Centers 5$5*Z  QZ "$Z[QZQ"$Q" [$5*ZQZ" $5*ZZQQZQ Q  QQ*$5*Z  [ZQ$5*[QQZ Q Q Z  [$5*QQQQ QQ [   Antibody Engineers ‰QZZ  Assay Biologists/Cellular Immunologists  ‰QQZZ  ZZZQ  Protein Scientists ‰QQQ  Q  QZ   Project Managers ‰QQZ Q  Q  5QQZ[QQQ QZZQQ 
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Governance "+4$ +4$ ["$QQ ZQQ5+4$QZ Q  Q  *Q#ZZQ [ "$QQ 5QQQQQQQQQ+4$Q Z$5*ZQQ+4$QQQQ *[  Q * Q [ZQ$5*Z *"$" +4$Z QQQQ +4$ QQQQ *%Z  Q  *Z+4$ QQ QZQ5+4$QQ *Z+4$ $5*Q  [QQQ$5*QQ$Q Z[ZZ"$  [QQ QZ
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 5Q$5*QZ QQQZQQ  QQ $5*+4$QQQQQ4QQ Z Sponsorship for postdocs/consultants. 5QQZ [ QQQ+4$QQQZ5 QQZQQ Q $5*ZQ5QQ Z+4$Q "$[ Access to Pfizer resources, including proprietary tools and technologies. 5$5*QQ +4$QQQQQQZZ QZQ5 Z  *5 QQZ 4Q[  In vitro QQZZ     In vivo Z # "" [   #Q& QZ QQZ Z Q  &Z &4Z   #QZZ #*"$ %4$ 4Q  9ZZQZ  Flexible funding to support preclinical and early clinical development activities. [ZQQ Q*QQZ+4$  QQ5*Q$5* "$QQQ Q QQQ*"$ZZ QZ[Q ZQQ
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Incentives for partners Acceleration of scientific progress 6Q[Z %QQQQQ   [ZQ  QZ  Q Q" [  *QQZQQQQQ $ Q "ZQ Q %Q*Q Financial incentives 8Q* QQQ QQ QZZ QQQ Q Q

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