The Model Tcurrent mechanism for escape Release of Synaptic inhibition Mapping Fixed points of mark outofphase bursting A function of Tcurrent inactivation parameters alone Stability ID: 231747
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Slide1
A method of determining the existence of bursting solutions, and output variables such as burst length and spike number, of multidimensional models using mapping.Slide2
The ModelSlide3
T-current mechanism for escapeSlide4
Release of Synaptic inhibition Slide5
Mapping
Fixed points of mark out-of-phase burstingSlide6Slide7
A function of T-current inactivation parameters aloneSlide8Slide9
Stability
has to be determined numericallySlide10
Parameter sensitivity analysis
depends on but does not
depends on but does notSlide11
Relaxing the assumptions
Half-center bursting: T-current inactivation threshold lies just beneath spiking threshold
Synaptic decay faster than spiking dynamics
Relaxing the half-center assumptions means that
h
as to be calculated numerically, and becomes discontinuous.
Nevertheless, the number of stable solutions increases.