PDF-haemophilia

of patients suffering from A and B has greatly improved during the past decade The prompt treatment of haemorrhages with plasma products containing the clotting factors that are lacking and the admin. of the . Efficacy of. Prophylactic Use . of . rFIXFc and . rFIX. . Products and . Simulation . of the . Effect . of . Compliance on Effectiveness. Alfonso . Iorio. , MD, PhD. 13 May 2014. A. lfonso Iorio,. 8.3. Starter. How many chromosome pairs do humans have?. 23 pairs. What are the sex chromosomes and how is it determined if a person is male or female?. X and Y. Male = XY, Female = XX. Do you know any conditions that are sex linked?. Sex linkage . and multiple alleles. Starter – sickle cell anaemia. Genotype. Hb. A. Hb. A. Hb. A. Hb. S. Hb. S. Hb. S. Phenotype. Normal. Sickle cell trait. Sickle cell anemia. Type of heamogolbin. Shaping the future of haemophilia togethe r Is this book for me?This book is intended for the parents of a child with mild or moderate haemophilia and for the children themselves when they are ready t Shaping the future of haemophilia togethe r Acquired HaemophiliaAdvice for people who have been diagnosed with acquired haemophilia Shaping the future of haemophilia togethe r IntroductionThis booklet Contents:. Introduction to sex linked inheritance.. Chromosome carries which type of genes?. Three types of traits. Characteristics of sex linkage.. Types of sex linkage.. Sex linked disorders.. Sex linked inheritance :. Dr C E du Toit. Groote . Schuur. Hospital. An inherited, X-linked, lifelong bleeding disorder affecting males almost exclusively. Factor VIII deficiency = Haemophilia A. Factor IX deficiency = Haemophilia B. Alfonso . Iorio. . MD, PhD. McMaster. University. Canada. BeneF. ix. ®. (. nonacog. . alfa. ) is . not currently approved . for once-weekly prophylaxis . treatment. Alfonso Iorio. Bayer, . Biogen. and . Immunogenicity. Peyman Eshghi. Prof. of Pediatric Hematology &Oncology. Pediatric Congenital Hematologic Disorders Research Center. Mofid. Children Hospital. Shahid Beheshti University of Medical sciences. Edin. ). Haemostasis-blood must be maintained in a fluid state in order to function as a transport system, but must be able to solidify to form a clot following vascular injury in order to prevent excessive bleeding, a process known as haemostasis. It is localised to the tissue damage and is followed by removal of the clot and tissue damage.. Factor X People with moderate to severe symptoms may also have bleeding:from the umbilical cord stump a�er a�er circumcisioninto jointsinto musclesinto the gut (gastrointes� perspectives . and . the Kenyan Situation. .. Dr. Festus . Njuguna. Moi. University/MTRH. INTRODUCTION. Genetic X-linked disorder. Haemophilia. A and B. Affects 1 per 10,000 deliveries. 30% of cases due to new mutations. Amy Crowther. What is Haemophilia?. Haemophilia is a coagulation disorder.. The responsibility of blood clotting is down clotting factors in the blood. People with haemophilia have low levels of Factor VIII and Factor IX.. Alfonso Iorio, MD, PhD. Health Information Research Unit & Hemophilia Program. McMaster. University. Canada. Alfonso Iorio. Biogen. . Idec . (Bayer, Baxter, . NovoNordisk. , Pfizer - No conflicts).