PPT-Why do patients bleed? Haemophilia

Professor Mike Laffan What can go wrong with haemostasis Haemostatic Plug Formation An Overview Vessel constriction Formation of an unstable platelet plug platelet adhesion platelet aggregation. Well 2 ries 120 las might Would He the and the dark did sun And ness Sav my in die ty Was Thus it might er head For for such crea crimes hide tures sin that my blu sa died 57375 6 man the worm have shing done face vote that cred migh For He While a brPage 1br IF A BLEED ARTWORK DESIGN FOR A 94mm Square BEER MAT PLEASE GIVE 3MM BLEED MAKING IMAGE AREA 100mm 94mm x 94mm Square Cutter 86mm image area if artwork has border Presentation designed by Wendy Gerstein, MD. Department of Medicine. NMVAHCS. Objectives. Recognize bleeding and level of severity.. Have a differential diagnosis for the bleeding.. Know how to stabilize the patient and stop the bleeding.. Sex linkage . and multiple alleles. Starter – sickle cell anaemia. Genotype. Hb. A. Hb. A. Hb. A. Hb. S. Hb. S. Hb. S. Phenotype. Normal. Sickle cell trait. Sickle cell anemia. Type of heamogolbin. Warfarin. Induced . Coagulopathy. : A Pilot Study. David . Barounis. , MD. 1. Catherine Knight, MD. 2. . Ben-Paul . Umunna. , MD. 2. Mary . Hormese. , . PharmD. , BCPS. 2. Elise Lovell, MD. 2. 1. Stanford University, Stanford, CA; . Shaping the future of haemophilia togethe r Acquired HaemophiliaAdvice for people who have been diagnosed with acquired haemophilia Shaping the future of haemophilia togethe r IntroductionThis booklet Dr C E du Toit. Groote . Schuur. Hospital. An inherited, X-linked, lifelong bleeding disorder affecting males almost exclusively. Factor VIII deficiency = Haemophilia A. Factor IX deficiency = Haemophilia B. Alfonso . Iorio. . MD, PhD. McMaster. University. Canada. BeneF. ix. ®. (. nonacog. . alfa. ) is . not currently approved . for once-weekly prophylaxis . treatment. Alfonso Iorio. Bayer, . Biogen. Bec. and Jessie. What is the cause of the disease?. It is caused by a defect in one of the genes that determines how the body makes blood clotting factor VIII or IX.. These genes are located on the X chromosomes. . ASCEND Randomized placebo-controlled trial of aspirin 100 mg daily in 15,480 patients with diabetes and no baseline cardiovascular disease Jane Armitage and Louise Bowman on behalf of the ASCEND Study Collaborative STOP THE BLEED Presentation By: Christina Dewberry-Heard RN,MSN,MBA Brookhaven College Nursing Brigham Wilcoxson District Emergency Manager 2 STOP THE BLEED Stop The Bleed is a National Campaign that started after the Sandy Hook School Shooting 2012: It’s mission is to educate people on what to do to prevent a person from bleeding to death. Stabilization!. How Common is GI Bleed? Why do we care about them? . . 300,000 hospitalizations annually in the U.S.. UGIB mortality rate 6 -10 %. Massive LGIB mortality rate 4 -10%. . Mortality increases in the elderly, patients with hepatic and renal dysfunction, CAD and malignancies (people usually die from another complication, NOT exsanguination).. Amy Crowther. What is Haemophilia?. Haemophilia is a coagulation disorder.. The responsibility of blood clotting is down clotting factors in the blood. People with haemophilia have low levels of Factor VIII and Factor IX.. Irish Haemophilia Society . C. onference, . Dunboyne. , September 2016. Niamh Murphy & Dr Lelia Thornton. Timeline of . haemophilia. treatment and hepatitis C and HIV infection. Hepatitis C and HIV Infection.