PPT-Clotting mechanism &coagulation profile

Platelets Thrombocytes Are small irregularly shapedoval non neocleated cells 23 µm in diameter derived from fragmentation of precursor megakaryocytes bone marrow The average lifespan of a platelet is between 8 and 12 days . I-. Deficiency of Coagulation Factors. II-. HYPERCOAGULABLE STATES . I-. Deficiency of Coagulation Factors. Treatment. AQUIRED DISORDERS. OF. BLOOD COAGULATION. ACQUIRED DISORDERS. OF. BLOOD COAGULATION. Tube Method . Mr. Mohammed A. Jaber. Coagulation Time ( Clotting Time) CT.. Clotting time was used as a screening test to measure all stages in the intrinsic coagulation system and to monitor heparin therapy .. Dr. . Mahvash. Khan. MBBS, MPhil. Occurs inside the blood vessels, it is also called fibrinolysis. Occurs due to a substance known as plasmin (. fibrinolysin. ). Plasmin is formed from plasminogen (. Guy Young, MD. Children’s Hospital Los Angeles. University of Southern California Keck School of Medicine. Abbreviations. Abbreviations will be explained the first time the term appears on a slide. Cardiovascular System: Blood Clinical Anatomy Tony Serino, Ph.D . Blood: Topic Objectives Be able to describe the physical properties of the blood including its components. Be able to explain how blood cells develop and what key ingredients are necessary in RBC development. Introduction. Blood—made up of plasma and formed elements. Blood—complex transport medium that performs vital pickup and delivery services for the body. Blood—keystone of body’s heat-regulating mechanism. Mehran Karimi MD. Tehran, September 14, 2017. Agenda. Background. Causes of bleeding and Clinical manifestations. Classification of coagulation disorders in neonates. Primary investigation and diagnostic evaluation. Dr. shatha Sami alyasrri. Assistant professor . Bleeding disorders during pregnancy and . delivery. . A. Inherited . Vascular abnormalities. Platelet disorders. Coagulation disorders. B.Acquired. Thrombocytopenia. According to Howell Theory of blood coagulation , the change of fibrinogen into fibrin is caused by thrombin which in fluid exists as prothrombin. The conversion of prothrombin to thrombin depends on the action of thromboplasin and calcium. . Professor . Dr.Noori. Mohammed . Luaibi. HEMOSTASIS EVENTS . The . term hemostasis means prevention of blood loss. Whenever a vessel is severed or ruptured, hemostasis is achieved by several mechanisms: (. antiphospholipid. syndrome. A short . tributededicated. to the memory of Dr. Virgil Woods Jr.: brilliant and generous scientist, dedicated mentor, and truly compassionate physician. by. Nunzio. Bottini, MD, PhD. Blood is a specialized mature liquid connective tissue.. Total blood volume- 6ltr. pH of blood- 7.4(slightly alkaline). Specific gravity- 1.055. Location- circulatory system. Blood plasma. Straw colored fluid. Dr. Mohammad Al-. Katari. Consultant Adult Hematology & Internal Medicine. King Khalid University Hospital – King Saud University. Outlines . Bleeding Disorders. Overview of Hemostasis.. Approach to the bleeding Pt.. Nervana. . Bayoumy. . Associate . Professor. Department of Physiology. . Objectives. At the end of this lecture . you . should be able to:. Recognize the different clotting factors. U. nderstand the role of calcium ions during clotting cascades..