PPT-Hemostasis and Blood Coagulation

Professor DrNoori Mohammed Luaibi HEMOSTASIS EVENTS The term hemostasis means prevention of blood loss Whenever a vessel is severed or ruptured hemostasis is achieved by several mechanisms . Abnormalities of Blood Coagulation. Learning Objectives. Describe functions of blood vessels and platelets in controlling bleeding. Explain three phases of coagulation and the respective factors involved. Guy Young, MD. Children’s Hospital Los Angeles. University of Southern California Keck School of Medicine. Abbreviations. Abbreviations will be explained the first time the term appears on a slide. Hematology Oncology Fellow. Hemostasis. Process of blood clot formation at site of vessel injury. Response must be. Quick. Localized. Carefully regulated. Phases of hemostasis. Formation of platelet plug. Coagulation Abnormalities in Infants and Children . Andrew J. Costandi MD, MMM . Children’s Hospital Los Angeles. USC Keck School of Medicine. Faculty Disclosures. None. Learning Objectives. Upon completion of this activity, participants will be able to:. Us / Mohammed Omballi . MSc. Hematology & immunohematology . The mechanism by which the blood kept in side . the blood . vessels in a fluid . state, . without clotting and stop bleeding . hemostasis. Hemostasis . is the . maintainence. of the clot-free state of blood & the prevention of blood loss via the formation of hemostatic plug. . Hemostasis . depends on three general components. :. . M. AND J. E. WYNANDS, M.D., C.IVI.~ THE V~Y F_~aLY STUVmS of this subject, many controversies existed regard- ing the various factors and mechanisms involved in the dotting process. One simply has to Dr. shatha Sami alyasrri. Assistant professor . Bleeding disorders during pregnancy and . delivery. . A. Inherited . Vascular abnormalities. Platelet disorders. Coagulation disorders. B.Acquired. Thrombocytopenia. According to Howell Theory of blood coagulation , the change of fibrinogen into fibrin is caused by thrombin which in fluid exists as prothrombin. The conversion of prothrombin to thrombin depends on the action of thromboplasin and calcium. . blood. . clots. as a . diagnosis. of . hypercoagulability. Nathalie . Westbrook. , Julien Moreau. . Biophotonics. group, Lab. Charles Fabry. in collaboration . with. Jean-Marc Allain. , . Adrien . Maureane Hoffman, MD, PhD. Professor of Pathology. Duke University Medical . Center. maureane@duke.edu. Hemostasis vs Thrombosis. Hemostasis. stops bleeding. Thrombosis. forms a blood clot in an artery or vein of a living person. The stoppage of . bleeding. or . hemorrhage. The normal . haemostatic. response; . to vascular damage depends on a closely linked interaction between the . blood vessel wall. , . circulating platelets. By . Dr. Sunita Mittal. Learning Objectives. Platelets Morphology. Hemostasis. Primary hemostasis. Platelet plug formation. Disorders of . p. rimary hemostasis. Secondary hemostasis. Disorders of secondary hemostasis. At the end of this unit of study, the student should be able to:. Compare the reference intervals for hemoglobin, hematocrit, erythrocytes, and leukocytes in infants, children, and adults.. Identify the function of erythrocytes, leukocytes, and platelets..