PPT-Sickle Cell Anemia Scott Hebert, MD

April 24 2017 What is SSD SSD is an autosomal recessive disorder of a point mutation in the beta globulin chain in hemoglobin SSD is an autosomal recessive disorder of a point mutation in the beta globulin chain in hemoglobin. b. d. g. a. a. Chromosome 16. Chromosome 11. 25%. 25%. a. a. b. d. g. 25%. 25%. 48%. 48%. 1.5%. 0.5%. 1.5%. 0.5%. Hemoglobin synthesis. a. a. a. a. a. a. b. g. d. b. d. g. HbA. HbF. HbA. 2. 98%. ~1%. Jenny Pham. Protein Structure & Function. Spring 2015. Outline. Normal Adult Hemoglobin (. Hb. A). Function: Deoxygenated v. Oxygenated. Mutation in . Hb. A. Sickle Cell Hemoglobin (. Hb. S). Sickle Cell Anemia. was developed to create a greater awareness in . the Nashville . community of Sickle Cell Disease and to raise . funds for . patient care, . social services. , and research. . All . proceeds from the event . Presenter: Bridget H. Wilson, Ph.D., MS, RN. Introduction. Sickle cell disease (SCD) pain continues to emerge among adolescents. Over 98,000 individuals are believed to have SCD within the United States. . Sickle Cell Trait. (Hereditary Condition) . Red blood cells (RBC’s) are normally round, circular or disc shaped.. RBC’s have hemoglobin component (helps carry oxygen) and platelets (helps in clotting). Ashley Jones-. Ragle. , MD. 12/10/2014. SICKLE CELL DISEASE. e.a. .. 24 year old . kurdish. female presents to . vumc. . ed. with severe back pain and left leg pain complicated by severe tachycardia (170s).. Dr. Soheila . zareifar. Department of pediatric hematology/oncology. Shiraz university of medical sciences. Qeshm. 2018. Transfusion in Sickle Cell. In sickle cell disease transfusions improve blood flow by reducing the proportion of red cells capable of forming sickle hemoglobin polymer. . ANEMIA . SUBJECTS. Kehinde. . M.O. 1. ., . Ogungbemi. S.I. 2. .,. . Anigbogu. C.N. 2. .,. . and . Jaja. . S.I. 2. . . 1. Department . of . Medicine, . 2. Department . of . Physiology, . College . (SCAFO). By Pastor Marcia Taylor, Founder, CEO. 2021. Our programs are specifically designed and dedicated to accommodating the needs of those who are faced with the challenges of Sickle Cell such as access to care, socio-economical support services, mental health, substance abuse, family and/or care provider educational support, and isolation. . a sign . of an underlying . disorder. There are several kinds of anemia. . A. . physiologic . approach classifies anemia according to whether. the deficiency in erythrocytes is caused by a defect in . Susan E. Kirk, MSPAS, PA-C. Instructor, Baylor College of Medicine. Texas Children’s Hematology Center. April 15, 2016. Texas Children’s Hospital Advanced Practice Provider Conference. Disclosures. Abeer. . Anwer. Ahmed. Sickle cell disease is a group of . haemoglobin. disorders . resulting from . the inheritance of the sickle β‐. globin. gene. . Sickle cell disease (SCD) is . an. . autosomal. Ass. Prof. . Abeer. . Anwer. Ahmed. Sickle cell . anaemia. Ass. Prof. . Abeer. . Anwer. Ahmed. Sickle cell disease is a group of . haemoglobin. disorders . resulting from . the inheritance of the sickle β‐. Disease Education 5/17 Care of patients with sickle cell disease for primary care providers and emergency room personnel Table of Contents Chapter 1: Background About Sickle Cell Disease and Making t