PPT-Toxicity of CNS Drugs: Anticholinergics, phenothiazine, TCA (CA)

Anticholinergic Poisoning with these drugs is less common than it was in former years Because these drugs are not used as frequently in drug therapy Ex Belladonna alkaloids and related atropine like drugs have been replaced with a different class of less toxic drugs H. By . Dr.. . Anjeannette. Reece. Introduction. AAPCC . National Poison Data System Annual Report . (2007). 1. :. 8. 8,582 . single exposures to anticholinergic . drugs. Unintentional . ingestions . – 83,352 . Dr. Naila Abrar. LEARNING OBJECTIVES. By the end of this session you should be able . to: . define . drug . toxicity;. know . the types of . toxicity;. comprehend . the reasons that may lead to toxicity of . Yolande Lucire and Christopher Crotty . . Why do some people believe that they do?*. What is the link between illicit street drug use and being diagnosed with “treatment-refractory schizophrenia”?. pg. 93 - 122. Gastrointestinal Drugs. Dr. . Dipa. . Brahmbhatt. VMD . MpH. , MS. dbrahmbh@yahoo.com. OBJECTIVES. Basic physiology that controls the GI tract. Mechanism of emesis and . antiemetics. 1. Objective 1: list the components of gastric juice that contribute to the pain associated with peptic ulcers. Objective 2: describe the physiology of gastric secretions. 2. Objective 3: list drugs considered to be ulcerogenic. What are antibiotics?. Definition: chemicals produced by one microorganism to kill or inhibit the growth of other microorganisms. Now included the semi-synthetic antibiotics. Effective against bacteria. Sharon Brown, RN. Toxicologic emergencies include acute poisonings and intake of drugs/alcohol.. 92% of these emergencies occurred in the home according to the American Association of Poison control in 2004.. Toxidromes. and . Toxidramas. Angelina . Pera. ED Registrar . Objectives:. . Understand the . basics. Classifying recreational drugs and their . toxidromes. Case scenarios of some common recreational drugs. -Lab SystemToxiLab is a trademark of Varian Contact at toxilabvarianinccom or 800-854-02776-monoacetylmorphineerythromycin ethylsuccinate EESphenobarbitolacetaminophenEsgic acetaminophen butalbital ca 4. th. Year Pharmacy. 2015-2016. PHENOTHIAZINE DERIVATIVES. The first-used class of efficacious antipsychotic agents – Chlorpromazine, the prototypical. member of this class, was first used to treat mental disease in 1951.. Introduction. Anticancer . drugs like doxorubicin (DOX) and mitoxantrone (MTX) are used to treat cancer. Nevertheless, they have worrying long-term toxicity. MTX and DOX cause cardiotoxicity and several risk factors could aggravate it. The aim of this work was to study the toxicity of clinically relevant MTX and DOX doses in infant (4 weeks), adult (3 months), and old (18-20 months) male CD-1 mice. . 4. th. Stage . Dr. Dalia . Abd. Al- Kader. PhD Pharmacology. Sympathomimetics. are stimulants that mimic the sympathetic nervous system.. produce a relative increase of adrenergic neurotransmitters at their sites of action. TRANQUILIZERS. Dr.Kumari. . Anjana. Assistant Professor. Deptt. . of Veterinary Pharmacology & Toxicology. Bihar Veterinary College, Bihar Animal Sciences University, Patna. Overview of the chapter . Brenda J. Gehrke, Ph.D.. Office of New Drugs/CDER/FDA. November 2016. Abbreviations. ADME. : absorption, distribution, metabolism, excretion. HU. : hydroxyurea. IB. : Investigator Brochure. ICH. : International Council for .