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Zoonosis diseases Dr.  Silvia Zoonosis diseases Dr.  Silvia

Zoonosis diseases Dr. Silvia - PowerPoint Presentation

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Zoonosis diseases Dr. Silvia - PPT Presentation

PessahEljay Zoonosis Disease Epidemiology Division Zoonosis Unit Feb 2015 SPessahEljay MD MPH MS Brucellosis Brucellosis Agent and transmission Agent Brucella sp Transmission ID: 779770

cases brucellosis division epidemiology brucellosis cases epidemiology division weeks data human national clinical years disease meat days cook case

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Presentation Transcript

Slide1

Zoonosis diseases

Dr. Silvia Pessah-EljayZoonosis Disease. Epidemiology Division

Zoonosis Unit. Feb, 2015

S.Pessah-Eljay

. MD., MPH., MS

Slide2

Brucellosis

Slide3

Brucellosis:

Agent and transmissionAgent: Brucella sp.

Transmission

Respiratory

Gastrointestinal

Wounded skin

Other (transfusion, transplants)

B.

canis

B.

pinnipediae

Slide4

Brucellosis:

Epidemiological cyclehttp://www.frontiersin.org/files/Articles/82508/fmicb-05-00213-HTML/image_m/fmicb-05-00213-g001.jpg

Slide5

Brucellosis:

Clinical manifestationsClassification according to the duration of the disease

1-8 weeks.

Acute or bacteraemia

9-52 weeks:

Subacute

> 52 weeks:

Chronic

The disease of the 1,000 faces

Incubation:

5 days to months

According to the clinical manifestations

With

Unspecific clinical symptoms:

Fever, chills, sweats

Weakness, fatigue, headache

Enlargement

of liver and spleenLynphadenopatiesDepresionJoint, muscle and back pain

With Specific clinical symptoms (localized):

Arthritis / Osteomyelitis (20-35%)

Genitourinary

infections (2-20%)

Neurobrucellosis

(3*5%)

Carditis

,

endocarditis (<2%)

Others

Slide6

Brucellosis:

Case definition

Slide7

National data of human cases. Epidemiology Division

Report is mandatory since 1951Passive surveillanceIn the last years there is no changes in the case definitionNumber of real cases are underestimatedBrucellosis:

National data of human cases. Epidemiology

Division

Slide8

National data of human cases. Epidemiology Division

Brucellosis: National data of human cases. Epidemiology Division

Slide9

Brucellosis:

National data of human cases. Epidemiology Division

Slide10

Brucellosis:

National data of human cases. Epidemiology Division

Slide11

Brucellosis:

National data of human cases. Epidemiology Division

Slide12

Brucellosis:

Treatment & PreventionPreventionAvoid unpasteurized dairy foods

Cook

meat thoroughly.

Cook all meat until it reaches an internal temperature of 145 to 165 F (63 to 74 C

)

Wear gloves.

Veterinarian, farmer, hunter or slaughterhouse worker, wear rubber gloves when handling sick or dead animals or animal tissue or when assisting an animal giving birth

Take safety precautions in high-risk

workplacesVaccinate

domestic animals

Treatment

Adults and > 8 years old:

Doxicyclin

200mg/kg/d x 6 weeks

+

Sreptomycin 1 gr/d x 2-3 weeks orRifampicine 600-900mg/d x 6 weeksChildren < 8 years old:CMX 2x8/40 mg/kg/d x 6 weeks +Sreptomycin

30 mgr/kg/d x 3 weeks

orRifampicine 15mg/kg/d x 3 weeksPregnant women:Doxicyclin 200mg/kg/d x 6 weeks +Rifampicine 600-900mg/d x 45 days or CMXWHO regimen