PPT-Bilirubin and Jaundice Presented By

AssistLecturer Aseel Ghassan Daoud MSc in PharmacyClinical L aboratory S ciences What is bilirubin It is a brownish yellow substance found in bile and it is produced during the breakdown of old RBCs then removed from the body through feces. Conclusions . . * . Jaundice indicates that there is an elevated concentration of bilirubin in serum.. * In neonates it is important to determine the concentration of unconjugated bilirubin in order to decide what treatment is required.. Disorders. Saul J. Karpen, MD, PhD. Professor of Pediatrics. Raymond F. . Schinazi Distinguished Biomedical . Chair. Division Chief, . Gastroenterology, . Hepatology & . Nutrition. Emory University School of . Overview. Definition. Production & metabolism. Measurement of . bilirubin. – serum & urine. Approach to the patient. Broad Differential Diagnosis. Work-up for “Medical” Jaundice. Work-up if Obstructive Jaundice. Pediatric Continuity Clinic Curriculum. Onyekachukwu Osakwe. Objectives. Recognize the common findings in newborns with . hyperbilirubinemia. . . Describe bilirubin metabolism. Distinguish between direct and indirect . Professor of Biochemistry and Clinical Biochemistry. . Faculty of Veterinary Medicine, . Moshtohor. , . Benha. University, Egypt.. E.Mail:Samyaziza@yahoo.com. JAUNDICE. . . Jaundice . (also called . . Rao. . M.Pharm. , (. Ph.D. ). Asst. . Professor . & HOD. Dept. . of Pharmacy Practice. Hindu college of pharmacy, . Gnt. , A.P.. Jaundice definition and facts. Jaundice. is a yellowish discoloration of the skin, mucous membranes and of the white of the eyes caused by elevated levels of the chemical . Germana. . Emerita. V. Gregorio, MD, PhD. Department of Pediatrics. University of the Philippines Manila. College of Medicine Philippine General Hospital. Objectives. Define and recognize the clinical features of jaundice. Objectives. Understand etiology and pathophysiology of neonatal jaundice and kernicterus. Identify high risk conditions. Understand limits of clinical exam. Describe appropriate evaluation. Apply appropriate treatment to term and near term infants. Dr.S.Parthasarathy. . MD DA . DNB. PhD FICA IDRA . Anatomy . Functions of liver . The liver is vital for. protein synthesis. glucose homeostasis . . bilirubin. excretion . toxin removal . Introduction. Definition. Epidemiology. Bilirubin . metabolism. Aetiopathogenesis. /Types. Clinical features. Evaluation of a jaundiced neonate. Management. Complications. Surgical/. C. holestatic. Dr. Muntadher Abdulkareem Abdullah. M.B.Ch.B,CABM,FIBMS,FIBMS(GE.&HEP.). At the end of this lecture , you must be able to answer these questions. Q1:. 22 year old male patient , with history of recurrent self resolving jaundice since childhood, presented with jaundice at the end of heavy duty day , otherwise the patient is healthy with nonsignificant other finding,. Alzoghaibi. , . Ph.D. zzoghaibi@gmail.com. Phone call, . WhatsApp. : 0506338400. Bilirubin. Bilirubin: is the end product of . heme. degradation derived from breakdown senescent (aging) erythrocytes by mononuclear phagocytes system specially in the spleen, liver and bone marrow. . Rashidy. Lecturer of General and Pediatric Surgery. Jaundice. Yellowish discoloration of body tissues & fluids (except the brain, CSF, tears, saliva & milk) due to excess . bilirubin. in the blood.. M.B.Ch.B,CABM,FIBMS,FIBMS(GE.&HEP.). Objectives:. At end of this lecture, the student should know :. 1.What is jaundice ?. 2. Types of jaundice?. 3. How you approach to each type of jaundice?. Jaundice.