PPT-Liver Function Tests (LFTs)

Measurement of Serum Bilirubin Total direct ampindirect TA Bahiya Osrah Bilirubin Bilirubin is the product of heme degradation 80 hemoglobin 20 other hemo protein as cytochrome. Simon . Lynes. Definition. Progressive destruction and regeneration of the liver parenchyma leading to fibrosis and cirrhosis. Aetiology. Vascular – Budd . Chiari. Infectious – viral hepatitis B and C. Jon . Bishop. Consultant Paediatric Gastroenterology. Starship Children’s Hospital. CF Liver Disease. Single . commonest non-respiratory cause of CF mortality. Various manifestations. Neonatal cholestasis. non-alcoholic fatty liver disease. Dr. . Abdulwahhab. S. Abdullah. CABM, FICMS-G&H. Alcoholic liver . disease. Alcoholic liver . disease (ALD) is . one of the most common causes of . chronic liver disease worldwide.. Pb. Emmanuel Obeng-Gyasi MPH, Ph.D.. Source—National . Institutes of Health . Background: Lead in gasoline. Major Source of Lead exposure. Belief . lead had the ability to boost engine performance by:. Liver and gastrointestinal disease. Physiological changes in pregnancy. Relaxation of smooth muscle resulting in:. decreased lower oesophageal sphincter pressure. decreased gastric peristalsis. delayed gastric emptying. Liver enzyme(ALT-AST-ALP-GGT). Liver is the largest Organ of the body weighing about 1.5 Kg.. Liver is called kitchen of our body.. Major Metabolic Functions of the Liver. Synthetic Function. Plasma proteins (albumin, globulins), cholesterol, triglycerides and lipoproteins. ALT&AST . T.A. Bahiya M. Osrah. Liver Functions. The liver is in the upper right part of the abdomen. . The functions of the liver include: . 1-storing glycogen (fuel for the body) which is made from sugars. . . . 1. .Metabolic Functions. :. U. rea cycle. Glycogen synthesis. Vitamin Metabolism. Minral Metabolism. Lipid Metabolism. Glycolysis. . . 2. .Excretory Functions. :. Cholesterol. Bile Pigments. William Alazawi MA(. Cantab. ) PhD MRCP. Senior Lecturer and Consultant in . Hepatology. Queen Mary, University of London. Does Liver Disease Matter?. Mortality in England & Wales. Liver-related mortality in under 65s. . . Shaimaa. . Munther. . Basic Anatomy. • liver unequally divided. into 2 lobes. • it has a dual blood supply. – Portal vein. – Hepatic artery. It has an excretory system for bile excretion. Dr Heather Lewis. Consultant . Hepatologist. . Imperial College Healthcare NHS Trust. The Lancet 2014. Mortality from liver disease in the UK. Liver function tests . vs. liver blood tests. Bilirubin, albumin and INR are the only blood markers of liver function. COL . MUHAMMAD ASIF NAWAZ . DEPARTMENT OF PATHOLOGY. ARMY MEDICAL COLLEGE, RAWALPINDI. Normal Liver Function. Protein synthesis and degradation: . albumin, transport proteins, clotting factors,. Carbohydrate metabolism. Julia Gore Thornton MD, MPH. Staff Gastroenterologist. Summa Health Medical Center. Borderline and Mild Elevation of Liver Tests. American Journal of Gastroenterology Jan 2017. Formal review and literature search. Each organ of the body has to perform its biochemical functions. Possible only when the cells of the organ are intact in structure and function. Any abnormality in the tissue caused by exogenous or endogenous factors will seriously impair the organ function which influences the health of the organism.