PPT-UNITIII LIVER FUNCTION TESTS

Each organ of the body has to perform its biochemical functions Possible only when the cells of the organ are intact in structure and function Any abnormality in the tissue caused by exogenous or endogenous factors will seriously impair the organ function which influences the health of the organism. – . 30, 2015. , Montréal, Québec. Hepatectomy. Risk Assessment:. CT . Volumetry. VS Nuclear Medicine. Disclosure . Statement: . No Conflict of Interest. May 28 . – . 30, 2015. , Montréal, Québec. The Progression of Chronic Liver Disease. Staging Is Based on the Amount of Hepatic Fibrosis, . O. r Is It?. Scoring Methods . for. . Stag. ing Hepatic Fibrosis. Hepatic Function vs Hepatic Fibrosis. Wilson disease is caused by mutations in the . ATP7B. gene. . This gene makes an enzyme that is involved in copper transport.. When the enzyme is mutated (not working properly) copper accumulates in the liver and brain and becomes toxic. History . In 1963, Dr Baruch . Blumberg. accidentally discovered an antigen that detected the presence of hepatitis B in blood samples.. Dr . Blumberg. and his team identified a strange antigen from a blood sample of an Austrian Aborigine.. Pb. Emmanuel Obeng-Gyasi MPH, Ph.D.. Source—National . Institutes of Health . Background: Lead in gasoline. Major Source of Lead exposure. Belief . lead had the ability to boost engine performance by:. Measurement of Serum Bilirubin (Total, direct &indirect) . T.A. Bahiya Osrah. Bilirubin. Bilirubin. is the product of . heme. degradation (80% hemoglobin, 20% other . hemo. -protein as . cytochrome. Liver enzyme(ALT-AST-ALP-GGT). Liver is the largest Organ of the body weighing about 1.5 Kg.. Liver is called kitchen of our body.. Major Metabolic Functions of the Liver. Synthetic Function. Plasma proteins (albumin, globulins), cholesterol, triglycerides and lipoproteins. ALT&AST . T.A. Bahiya M. Osrah. Liver Functions. The liver is in the upper right part of the abdomen. . The functions of the liver include: . 1-storing glycogen (fuel for the body) which is made from sugars. . . . 1. .Metabolic Functions. :. U. rea cycle. Glycogen synthesis. Vitamin Metabolism. Minral Metabolism. Lipid Metabolism. Glycolysis. . . 2. .Excretory Functions. :. Cholesterol. Bile Pigments. . . Shaimaa. . Munther. . Basic Anatomy. • liver unequally divided. into 2 lobes. • it has a dual blood supply. – Portal vein. – Hepatic artery. It has an excretory system for bile excretion. Dr Heather Lewis. Consultant . Hepatologist. . Imperial College Healthcare NHS Trust. The Lancet 2014. Mortality from liver disease in the UK. Liver function tests . vs. liver blood tests. Bilirubin, albumin and INR are the only blood markers of liver function. An 8-year-old boy presents with three days history of abdominal pain lasting ~20 min. It occurs before breakfast & sometimes at school, where it will generally pass when . . he busies himself with activities. He has a tendency to constipation. His pains worsen when faced with tests at school or other stressors. Exam is normal. BY . Dr.Qutaiba. . Abdulkareem. . Qasim. . PhD. . In Clinical . Biochemistry. FUNCTIONS OF THE LIVER. General metabolic functions :. 1-. . Glycogenesis. and . glycogenolysis. 2-. . Gluconeogenesis. Julia Gore Thornton MD, MPH. Staff Gastroenterologist. Summa Health Medical Center. Borderline and Mild Elevation of Liver Tests. American Journal of Gastroenterology Jan 2017. Formal review and literature search.