PPT-Estimation of Serum Bilirubin (Total & Direct)

Objective To estimate the amount of bilirubin in serum Bilirubin It is a by product of the breakdown of hemoglobin Yellow color Bilirubin Types of Bilirubin Direct bilirubin . Function. Dr. . Baghbanian. M.. Gastroenterologist. Shaheed. . Sadoughi. hospital / 2012. . liver tests. (. 1) detect the presence of liver . disease. . (2) . distinguish . different types of liver . . Dr. Ravi Kant. Assistant Professor. Department of General Medicine. Introduction. Jaundice or . icterus. , is a yellowish discoloration of tissue resulting from the deposition of . bilirubin. .. Tissue deposition of bilirubin occurs only in the presence of serum . Measurement of Serum Bilirubin (Total, direct &indirect) . T.A. Bahiya Osrah. Bilirubin. Bilirubin. is the product of . heme. degradation (80% hemoglobin, 20% other . hemo. -protein as . cytochrome. Pediatric Continuity Clinic Curriculum. Onyekachukwu Osakwe. Objectives. Recognize the common findings in newborns with . hyperbilirubinemia. . . Describe bilirubin metabolism. Distinguish between direct and indirect . Assist.Lecturer. Aseel. . Ghassan. . Daoud. M.Sc. in Pharmacy/Clinical . L. aboratory . S. ciences. What is bilirubin?. It is a brownish yellow substance found in bile and it is produced during the breakdown of old RBCs then removed from the body through feces.. Shemeri. (M.SC. Clinical Biochemistry) . At a Glance. Why . Get Tested?. To screen for or monitor . liver disorders. When to Get Tested?. If your doctor thinks you have signs or symptoms of liver damage, liver disease, bile duct blockage, . Dr. . shaghayegh. . Moradi. . Almdarloo. Pregnancy is associated with many normal physiologic and anatomic changes that must be considered in the diagnosis of hepatobiliary diseases. . Physical examination. Rawashdeh. , MD, . MSc. , FRCP, FRCPCH. Professor of Pediatrics . & . Gastroenterology. Jaundice: Definition. Yellow staining of the skin and sclera by abnormally high blood levels of the bile pigment . DMSO Colorimetric For in - vitro diagnostic use only Store at 2 - 8  C INTENDED USE For the quantitative determination of total bilirubin concentrationin human serum or plasma. CLIN ICAL SIGNIFIC DIRECT BILIRUBIN OSR6111 4 x 6 mL R1 Color Reagent (DBILC) OSR6211 4 x 20 mL R1 Color Reagent (DBILC) 4 x 20 mL R1 Blank Reagent (DBILB) OSR6511 4 x 107 mL R1 Color Reagent (DBILC) ISSN: 2279 - 0853 Volume 1 , Issue 3 (Sep - Oct. 2012), PP 17 - 28 www.iosrjournals.org www.iosrjournals.org 17 | Page Review on “Evolution of Methods of Bilirubin Estimation” Dr . Dr. Muntadher Abdulkareem Abdullah. M.B.Ch.B,CABM,FIBMS,FIBMS(GE.&HEP.). At the end of this lecture , you must be able to answer these questions. Q1:. 22 year old male patient , with history of recurrent self resolving jaundice since childhood, presented with jaundice at the end of heavy duty day , otherwise the patient is healthy with nonsignificant other finding,. Junior resident. Dept. Internal . M. edicine. Jaundice. Yellowish discoloration of . body tissues resulting . from the deposition of bilirubin.. Tissue deposition occurs only in the presence of serum hyperbilirubinemia and is a sign of either liver disease ,haemolytic . Each organ of the body has to perform its biochemical functions. Possible only when the cells of the organ are intact in structure and function. Any abnormality in the tissue caused by exogenous or endogenous factors will seriously impair the organ function which influences the health of the organism.