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For the Urologist by the Urologist: Essential Concepts in M For the Urologist by the Urologist: Essential Concepts in M

For the Urologist by the Urologist: Essential Concepts in M - PowerPoint Presentation

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Uploaded On 2017-01-26

For the Urologist by the Urologist: Essential Concepts in M - PPT Presentation

Goals Case Study Newly Diagnosed Low Volume Metastatic Disease CHAARTED Benefit of Docetaxel Toxicity Grade 3 AE or Greater Treating the Primary Tumor Case Study Continued Abiraterone COUAA302 Trial ID: 514077

case treatment study considerations treatment case considerations study urologist trial abiraterone biomarkers enzalutamide mcrpc

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Presentation Transcript

Slide1

For the Urologist by the Urologist: Essential Concepts in Managing mCRPCSlide2
Slide3

GoalsSlide4

Case Study: Newly Diagnosed Low Volume Metastatic DiseaseSlide5

CHAARTED: Benefit of DocetaxelSlide6
Slide7

Toxicity Grade 3 AE or GreaterSlide8

Treating the Primary TumorSlide9

Case Study, ContinuedSlide10

Abiraterone COU-AA-302 TrialSlide11

Enzalutamide PREVAIL TrialSlide12

Treatment Considerations: Use of Immunotherapy Slide13

Sipuleucel-TSlide14

Treatment Considerations: Abiraterone vs EnzalutamideSlide15

Case Study: mCRPC Progressing Through Second Generation Androgen Axis InhibitorsSlide16

Further Treatment ConsiderationsSlide17

Emerging BiomarkersSlide18

Biomarkers: Mutations of DNA Repair and High Rate of Response to OlaparibSlide19
Slide20

CabazitaxelSlide21

ConclusionsSlide22

Remaining Questions