PPT-Genetics disorders-2 N umerical changes in chromosome numbers:

Aneuploidy Variation of a certain chromosome with in the set Hyperploidy gain of chromosome Trisomy 2n1 Double trisomy 2n11 Tetrasomy 2n2 Hypoploid y loss of chromosome Monosomy 2n1. Also its possible for otherwise healthy people to develop severe illness so any one concerned about their illness should consult their doctor There are emergency warning signs that should signal anyone to seek medical care urgently Emergency Warning By: Keith King. Objectives. State the history of genetics;. Describe major century events;. Define terms used in genetics . History of Genetics. People have known about inheritance for a long time.. --children resemble their parents. The Big Epigenetic Event. Males – 46,XY. Females – 46,XX. Compensate for gene dosage, all mammals inactivate extra X chromosome. Discovered by Mary Lyon. Lyon, M.F., 1961. Gene action in X-chromosome of the mouse (. BY: Brandon. a. nd . Kellen. The odds of having a child with a chromosome disorder/syndrome is 1 in 160 live births. (.00625%). Approximately half of these births will end up being a miscarriage. . The bacterial chromosome is a double-stranded, circular DNA molecule associated with a small amount of protein. Eukaryotic chromosomes have linear DNA molecules associated with a large amount of protein. Subject to National cap or supply and demand model.. Regional allocation numbers include joint ATR applications.. Agreed Regional allocation numbers may not be fully approved.. Overview. Serious health issues can occur when there are problems with an organisms DNA.. Objectives:. 1. What is a karyotype? . 2. What is nondisjunction?. 3. Distinguish between the . chromosomal alterations. Polydactyly. Down Syndrome. Hemophelia. Progeria. Hypertrichosis. Sickle Cell Anaemia. INTRODUCTION. What is genetic diseases/disorders?. The human body is composed up of cells , each one specializing a particular function like sensing light, smelling . 41. Learning Objectives—Level I. At the end of this unit of study, the student should be able to:. Define . chromosome. and . mitosis. .. List the basic steps of cytogenetic analysis, and select the most appropriate type of specimen for analysis of suspected constitutional and neoplastic (acquired) disorders.. --children resemble their parents. --domestication of animals and plants, selective breeding for good characteristics. --Sumerian horse breeding records. --Egyptian data palm breeding. Early ideas about genetics. Hippocrates:. Pangenesis. Particles (. pangenes. ) from each part of the body moved to the egg and sperm. Changes in organisms over their lifetime would be passed on to offspring . INFORMATION COMPLEX LEARNING DIFFICULTIES AND DISABILITIES RESEARCH PROJECT (CLDD)The term, ‘rare chromosome disorders’, refers to conditions which:1. occur due to missing, duplicated o ISPG Residency Education Taskforce. Introduction. What does genetics have to do with psychiatry?. - psychiatric illnesses run in families. - the major psychiatric disorders have a high heritability. Euploid. Have the . normal. chromosome number. Polyploid. A cell with . extra sets. of chromosomes. Ex: triploid (3n). Aneuploid. Cells missing a single chromosome or having an extra chromosome. Alterations in Chromosome Number.