PPT-Chromosome Analysis of Hematopoietic and Lymphoid Disorders

41 Learning ObjectivesLevel I At the end of this unit of study the student should be able to Define chromosome and mitosis List the basic steps of cytogenetic analysis and select the most appropriate type of specimen for analysis of suspected constitutional and neoplastic acquired disorders. Also its possible for otherwise healthy people to develop severe illness so any one concerned about their illness should consult their doctor There are emergency warning signs that should signal anyone to seek medical care urgently Emergency Warning 1 Hematopoietic and Lymphoid Neoplasm Coding ManualEffective with Cases Diagnosed 1/1/2010 and ForwardPublished January 2015In Appreciation Editors: Jennifer Ruhl, MSHCA, RHIT, CCS, CTR, NCI SEERMarga Genetic disorders can be due to any of the following factors:. A. Monogenetic Disorders: Caused by a mutation in a single gene. Autosomal. recessive alleles:. a. You may be a carrier and not know it, since the dominant allele masks the recessive.. SUBMITTED BY:. ALABADO, SHEENA ANN C.. LUISTRO, JANELLE. What is a chromosome?. A chromosome is…. A very long DNA molecule and associated proteins that carries portions of the hereditary information of an organism.. Transplantation . Apheresis and Mobilization . Donna . F. erguson, M.D.. July 16, 2015. History . Overview. Stem cell transplantation . HPC, Apheresis . HPC, Bone marrow . Autologous . Allogeneic . Donor and recipient . Overview. Serious health issues can occur when there are problems with an organisms DNA.. Objectives:. 1. What is a karyotype? . 2. What is nondisjunction?. 3. Distinguish between the . chromosomal alterations. What happens if mistakes occur?. Nondisjunction. When chromosomes fail to separate in meiosis. Lead to chromosomes disorders. Karyotype. Is an organized profile of a persons chromosomes. Two chromosomes specify gender:. Prof Ivy A E . Ekem. 16. th. September 2016. Blood. en.wikipedia.org / M. . Komorniczak. . Accessed 08.09.16. Development of blood cells. en.wikipedia.org. Site of blood formation. www.healthline.com>Ref Library. Chromatin – the less tightly coiled DNA-protein complex. Centromere – the region of the chromosome that holds the two sister chromatids together during mitosis.. SEX CHROMOSOMES & AUTOSOMES. Sex chromosomes are chromosomes that determine the sex of an organism, and they may also carry genes for other characteristics. . Primary lymphoid tissue. : Bone marrow, Bursa of fabricius, Thymus.. Secondary lymphoid tissue. : Lymph node, Spleen.. Tertiary lymphoid tissue. : Mucosa-associated lymphoid tissue, Intra-epithelial lymphocytes.. INFORMATION COMPLEX LEARNING DIFFICULTIES AND DISABILITIES RESEARCH PROJECT (CLDD)The term, ‘rare chromosome disorders’, refers to conditions which:1. occur due to missing, duplicated o Immune System. (organs). Dr. Mustafa Jawad. Introduction. . The immune system comprises a variety of organs which are concerned with growth . and development . of immunocompetent cells. These are lymphoid . Euploid. Have the . normal. chromosome number. Polyploid. A cell with . extra sets. of chromosomes. Ex: triploid (3n). Aneuploid. Cells missing a single chromosome or having an extra chromosome. Alterations in Chromosome Number. Chromosome 2A. Chromosome 2B. Chromosome 3A. Chromosome 3B. Chromosome 4A. Chromosome 4B. Chromosome 5A. Chromosome 5B. Chromosome 6A. Chromosome 6B. Chromosome 7A. Chromosome 7B. Chromosome 8A. Chromosome 8B.