Bone Neoplasm Benign Malignant differentiation Location Margins of lesion Sharp narrow zone of transition not aggressive Fuzzy wide zone of transition aggressive Matrix appearance of contents ID: 492658
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Bone NeoplasmSlide2
Bone Neoplasm
Benign – Malignant differentiation
Location
Margins of lesion
Sharp = narrow zone of transition = not aggressive
Fuzzy = wide zone of transition = aggressive
Matrix – appearance of contents
Chondroid
– cartilage like
Osteoid
– bone like
MixedSlide3
Non-ossifying Fibroma
Well defined sclerotic margin
Internal septationsSlide4
Non Ossifying
Fibroma
Sharp demarcation
Benign appearingSlide5
Enchondroma
Phalanx
Sharp margins
Typical location
Benign processSlide6
Osteogenic Sarcoma
Destructive lesion in the distal femur (arrowheads)
Permeative – ‘broad zone of transition’
Extends into the medial soft tissues
Zone of periosteal reaction along proximal femur (arrows)Slide7
Parosteal
Osteogenic
SarcomaSlide8
Metastatic Breast Cancer
Destructive lesion of the proximal humerus
History of breast carcinoma