PPT-Cell injury, adaptation and death

Unite one Second Lab The two lung abscesses seen here are examples of liquefactive necrosis in which there is a liquid center in an area of tissue injury One abscess appears in the  upper lobe . Grace Denton & Stephanie . Tristram. G.E.Denton@warwick.ac.uk. S.C.Tristram@warwick.ac.uk. What are some of the causes of cell injury and cell death?. Causes of cell injury .  . CHIPING: C. Causes of cell injury. Hypoxia (oxygen deprivation). Occurs due to. . Loss of blood supply - . Ischaemia. . Inadequate blood supply. . Loss of oxygen carrying capacity – . anaemia. Physical agents. Four Stages in Skin Healing. Inflammation. Blood flow increases. Phagocytes attracted. Scab formation. Cell division and migration. Scar formation. Bleeding occurs at the site of injury immediately after the injury, and mast cells in the region trigger an inflammatory response.. School of . Pharmacy. 29-39 Brunswick square. WC1N 1AX. UCL Drug discovery group application note.. Author: . Dr.. Ben Allsop. Cell toxicity assays. *Data in this presentation are owned by the UCL DDG and are not for unauthorised reproduction*. J. Matthew Velkey. matt.velkey@duke.edu. 454A Davison, Duke South (green zone). Cellular Adaptation to Injury or Stress. Injury or Stress. Increased demand. Decreased stimulation or lack of nutrients. . ADAPTATION . TO ENVIRONMENTAL STRESS. Lab:2&3. Proliferative endometrium . A. . A section of the uterus from a woman of reproductive. . age reveals a thick endometrium composed of proliferative glands in an abundant . National . Center for Health Statistics. Presented . at the . National Conference on Health Statistics. August 6, 2012. Washington, DC. Tools, techniques and framework for the analysis of vital statistics data on external causes of injury death. Assist.Prof.Dr. . . Baydaa. . H.Abdullah. Reversible . cell injury . . It . is called also . degeneration . .It is accumulation of normal substances (glycogen ,water) or abnormal (. Amyloid. ) inside the cell due to injury agent. classified into two main groups . of membrane integrity and leakage of cellular content ,largely resulting from the degradative action of enzymes on lethally injured cells. The enzymes responsible for digestion of the cell may be derived from the lysosome of dying cells themselves and from lysosomes of leukocytes cells. 3. rd. stage . . . Cellular injury. Cellular injury . can occur in a number of different ways. The extent of injury that cells experience is often related to the intensity and duration of exposure to the injurious event or substance. Cellular injury may be a reversible process, in which case the cells can recover their normal function, or it may be irreversible and lead to cell death. . . Cellular. . Responses. . to. Stress and . Noxious. . Stimuli. Sequence. . of. . reversible. . cell. . injury. and . cell. . death. . . Necrosis. and . apoptosis. are the . two. major . D. r Mays Ibrahim . C. ell injury and adaptation . learning objectives:. introduction . to pathology. knows the type of cell response to stress and injury . be able to define adaptation and its types . 1- Necrosis. 2- Apoptosis. 3-Gangreen. 4-Pathological calcification . 1. Necrosis . is . irreversible cell . death . characterized by loss of membrane . integrity and leakage of cellular contents . culminating in .