PPT-Lecture 6 Delivery of proteins

Alternative routes of administration Alternative Route of Administration Parenteral administration has disadvantages needles sterility injection skill compared to other possible routes. Currently nasal drug delivery technology using chitosan to speed the absorption of the API shows great potential with several applications in clinical trials Nonviral gene delivery systems using chitosan as a carrier are also the subject of intense Web: . pollev.com/. ucibio. Text: . To: 37607. . Type in: 169964 <your question>. The importance of structure. “Chaperones” & protein folding. Misfolded. proteins are very, very bad!. Richard Addo, . R.p. h. .,. . p. h.D. ASSOCIATE PROFESSOR. UNION UNIVERSITY SCHOOL OF PHARMACY. JACKSON TENNESSEE USA. outline. Structure of eye and different pathways of ocular administration. Challenges for ocular delivery of proteins/peptides. Soma . Mukherjee. SMU,Chemistry. 5. th. April’2011. Introduction : Protein & important structural features for therapeutics.. Development. Classification. Examples of Protein as targeted delivery device. Presented by:. . Sk.Asma. . Shaheda. ? ?. ? ?. What is a silk based delivery. proteins of milk, meat and eggs.. Milk composition. Deficient in iron and vitamin C. Milk proteins. Total protein content in milk – 2.9 – 3.5%. Two major types of milk protein. Caseins (80%). Whey proteins: (20%). Proteins are polymers of amino acids produced by living cells in all forms of life.. A large number of proteins exist with diverse functions, sizes, shapes and structures but each is composed of essential and non-essential amino acids in varying numbers and sequences.. Prokaryotic and Eukaryotic Chromosomes Organization . Dr.Sawsan. . Sajid. . - The . term chromosome comes from the Greek words for color (. chroma. ) and body (soma). Scientists gave this name to chromosomes because they are cell structures, or bodies, that are strongly stained by some colorful dyes used in research. proteins of cereals and legumes.. Cereals . http://jxb.oxfordjournals.org/content/53/370/947.full.pdf+html. Cereals are the . most important crops in the . world. Basic food in European countries.. . Protein Isolation and Quantification . How to isolate total protein. Lyse. the cell. Solubilize. the protein. For . solubilize. membrane protein, we have to use detergent in protein extraction buffer. . Nutritive function of . proteins.. Quality evaluation.. Proteins: a major food macro-component. . Food is the major source providing proteins to human body:. . food with animal origin. food with . plant. GE. By. MSc. . Elham. . Faisal. MSc.Wafaa. . Ajam. Analytical chemistry(practical) . Ministry of higher education and scientific research. AL-. Mustaqbal. University college . Department of medical physics. Mukherjee. SMU,Chemistry. 5. th. April’2011. Introduction : Protein & important structural features for therapeutics.. Development. Classification. Examples of Protein as targeted delivery device. Size. Colloidal solutions. Charge. UV absorption. Solubility. Physical properties. Molecular weight. :. Vary from. 6000 . to million Daltons (Da) . Protomeric. proteins. : 50. . 000 . to. 100. .