PPT-Amides

BY Jacob Baird and Nathan Carrier Structural components Carbonyl Carbon pi bonded to oxygen httpsuploadwikimediaorgwikipediacommons446IUPACcarbonyldivalentgrouppng Structural components continued. Chapter 19. Carboxyl Derivatives. In this chapter, we study three classes of compounds derived from carboxylic acids; anhydrides, esters, and amides.. Each is related to a carboxyl group by loss of H. Chapter 1.7 Amines and Amides • An amine is an organic compound, related to ammonia, that contains a nitrogen atom bonded to one or more alkyl groups on each molecule • An amide i 20-1. Carboxylic acid derivatives undergo substitution reactions via the (often acid- or base-catalyzed) addition-elimination sequence:. The relative reactivities of the substrates follow a consistent order:. A-7 N Li O 1 N N N Li2 N Li Ph 3 O N 4Li N N 5Ph N Li Ph 6 A-8of chiral lithium amides Tylenol, an aspirin substitute, contains acetaminophen. Acetaminophen is an amide; it acts to reduce fever and pain; however, it has little anti-inflammatory effect.. Learning Goal . . Draw the amide product from . In a reverse reaction of . amidation. , hydrolysis occurs when water and an acid or a base split an amide.. Learning Goal . Write balanced chemical equations for the hydrolysis of amides.. Acid Hydrolysis of Amides. Nucleophilic Acyl Substitution. 2. Carboxylic Acids and . Their Derivatives. Carboxylic Acid Derivatives:. Acid Halides. Acid Anhydrides. Types of anhydrides. :. Cyclic esters. Types of amides. Cyclic amides. . Instructor. Dr. Upali Siriwardane (Ph.D. Ohio State) . E-mail: upali@chem.latech.edu . Office. : 311 Carson Taylor Hall ; Phone: 318-257-4941;. Office Hours. : . MWF 8:00 . am - . 10:00 . am; . Amines and Amides. Bonding . Characteristics of . Amines & Amides. . . Hydrocarbons . compounds . containing nitrogen are . the focus of . the chapter 17 on . amines . Amines are derivatives of ammonia molecules that contain a nitrogen atom bonded to one or more alkyl groups on each molecule.. . Many amines have strong, unpleasant odours.. . ex. putrescine. cadaverine. Book chapter: 14. Pages: 472-511. Carbon atom of a carbonyl group is attached to a hydroxyl group forming a carboxyl group. As functional group – attached to an alkyl group or an aromatic group. IUPAC names. A. Block Nerve Conduction. B. Sensory and Motor Nerves. C. Reversible. Local Anesthetics- MOA. Blockade of Voltage-Dependent . Na. +. Channels. B. . . Site at Cytoplasmic End of Channel. C. . . Write the common and IUPAC names for amides and the products of formation and hydrolysis.. Tylenol, an aspirin substitute, contains acetaminophen. Acetaminophen is an amide. It acts to reduce fever and pain; however, it has little anti-inflammatory effect.. Transition Metal . Catalyzed . Amide . B. ond . F. ormation. - May, 11. th. 2016 -. Table of contents. Introduction. Generalities about amides. Metal Catalyzed C-N . bond formation. Ru-catalyzed conversion of alcohol and aldehydes into amides.