PPT-Genomic evaluations and

breed composition for crossbred US dairy cattle Introduction Traditional evaluations are on allbreed base Pedigree breed composition PBC has been computed distributed and used to calculate heterosis since we went to the allbreed model in . Fikret Isik. Associate . Professor. September 16, 2013. Genomic BLUP - UofCopenhagen. 1. Cooperative Tree Improvement Program. North Carolina State University, Raleigh, . USA. Outline. Background. Realized genomic relationships. Early genomic theory. Nejati-Javaremi. et al (. 1997. ) tested use of genomic relationship matrix in BLUP. Meuwissen et al (. 2001. ) tested linear and nonlinear estimation of . haplotype. effects. Comm. 301. Reasons for changes in SNP set. History. Single list created across breeds. Poor performing SNPs removed. SNP selection criteria changed. Updated assembly changed SNP locations. Additional QTLs as . A “big data” project of the . Animal Genomics and Improvement Laboratory (AGIL). AGIL mission. Discover and develop improved methods for the genetic and genomic evaluation of economically important traits of dairy animals and small ruminants. Abstr. . 16462. Causative variants. Benefits of knowing causative variant. Supports an exact test . (particularly useful for undesirable conditions). No linkage decay when used in evaluation . Increased reliability of genomic evaluations as causative variants replace less informative SNP. K.L. Parker Gaddis,. 1. M.E. Tooker,. 2. J.R. Wright,. 2. J.H. Megonigal, Jr.,. 1. J.S. Clay,. 3 . J.B. Cole,. 2. and P.M. VanRaden. 2. 1 . Council on Dairy Cattle Breeding, Bowie, Maryland, USA. Abstract #461. Background - Crossbreeding. Harris and Johnson (2010) . used multibreed relationship matrix to obtain GEBVs in NZL. Olson et al (2010) . estimated MT multi-breed SNP effects and genomic breed composition. March 2012 AIPL Update Topics Genomics overview April 2012 changes Accounting for bias Selection index adjustments Cow adjustments Calving traits update Whole-genome selection Use many markers to track inheritance of chromosomal segments A “big data” project of the . Animal Genomics and Improvement Laboratory (AGIL). AGIL mission. Discover and develop improved methods for the genetic and genomic evaluation of economically important traits of dairy animals and small ruminants. George Wiggans, CDCB Technical Advisor. Highlights of U.S. system. Over half a million animals genotyped in 2016. 67% of AI breedings to genomic bulls. Genomic relationship between genotyped cows and marketed bulls available. Dairy Cattle. 9 million cows in US. Attempt to have a calf born every year. Replaced after 2 or 3 years of milking. Bred via AI. Bull semen collected several times/week. Diluted and frozen. Popular bulls have 10,000+ progeny. 1 Agilent DNF - 4 8 8 HS Kit Quick Guide for the Fragment Analyzer Systems The Agilent Fragment Analyzer systems are automated capillary electrophoresis platforms for scalable, flexible, fast, and Dr. Breno Fragomeni. Assistant Professor. Animal Science - UConn. Where are the labels?. Introduction . Why genomic prediction?. Higher accuracy. Shorter generation interval . Higher genetic gain. Genetic gain per year. biology – lessons from dairy cattle breeding. Dairy Cattle. 9 million cows in US. Attempt to have a calf born every year. Replaced after 2 or 3 years of milking. Bred via AI. Bull semen collected several times/week. Diluted and frozen.