PPT-The Increasing Use of Targeted Therapies for Leukemia and Lymphoma

Shira Dinner MD Northwestern University Educational Objectives Define terminology used regarding leukemia Describe the latest developments in the treatment of acute lymphoblastic leukemia ALL. Rita All. Carrie Warner. Definition. Leukemia is a group of malignant diseases that result in changes to circulating lymphocytes characterized by diffuse, abnormal growth of . leukocytic. precursors in the marrow.. Stuart S. Winter, MD. Pediatric Hematology/Oncology. The T. John Gribble Endowed Chair. Background- Acute Lymphoblastic Leukemia in Children & Young Adults. Risk Classification Strategy. Through improved approaches to risk classification, therapy intensification, and supportive care, children and young adults with acute lymphoblastic leukemia (ALL) have an overall survival rate that currently exceeds 80%. David Houghton BPharm MSc GPhC. Oral Complications in Cancer and Palliative Care. Monday . 12 May 2014. Definition:. Stomatitis – general term : includes inflammation and ulceration of mucosal lining from any cause. a closer look . SEER HEMATOPOIETIC DATABASE. Understanding the disease. AMBIGUOUS TERMS. Choosing . the right . Histology & TOPO CODE . Navigation of the Hematopoietic and Lymphoid Neoplasm Database . Hiba . El Hajj, Ph.D.. Assistant Professor, . Departments . of Internal Medicine. AND Experimental . Pathology, Immunology and Microbiology. Faculty of Medicine. American University of . Beirut. 1. L’OREAL-UNESCO. Sima Jeha, MD T-cell Neoplasms Chronic Myelomonocytic Leukemia ASXL1Juvenile Myelomonocytic Leukemia PTPN11 disease or mutation Germline CBL mutation Myeloid/Lymphoid Neoplasms PDGFRA rearrangement often del4q12q1 Geoff Cuvelier MD FRCPC. Pediatric Oncologist. CancerCare. Manitoba. Associate Professor, . Dept. of Pediatrics and Child Health. University of Manitoba. Canadian Association of Physician Assistants Conference . VCR VOICE Hodgkin Lymphoma (HL): most common sites are in the chest, neck, or under the arms. Hodgkin lymphoma most o�en spreads through the lymph vessels from lymph node to lymph node. Ra in the marrow to mature or may travel to other parts of the body to mature. Normally, ontrolled way, as the body needs them. Some and lymph vessels. Some reside in the lymphatic tissues that are prim E4 I CUTIS ® of mature T lymphocytes associated with infection by human T-lymphotropic virus 1 (HTLV-1), which is increasing in incidence in areas of the United States with large immigrant popula Overview Case 3 • 59 year old man with lymphadenopathy in the neck, supraclavicular area, inguinal area . He states that he has had LN for at least 18 months and they have waxed and waned . Introduction to Leukemia. Definition. Historic Perspective. Etiology and Risk Factors . Incidence. Classification. Comparison of Acute and Chronic Leukemia. Leukemia. Definition. Leukemia is a malignant disease of hematopoietic tissue characterized by the accumulation abnormal white cells (neoplastic or leukemic) in the bone marrow leading to bone marrow failure, a raised circulating white cell count (leukocytosis) and infiltrate organs (e.g liver, spleen, lymph nodes, brain) . How they work and the future of medicine. Every cell has a set lifespan. After that lifespan has been reached, a cell undergoes apoptosis (programmed cell death). The life(span) of a cell. How does apoptosis work?.