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MUBI MultiModal Ultrasound Breast Imaging Research Platform


J Camacho J F Cruza N Gonzlez-Salido M Prez-Liva JL Herraiz JM UdasUltrasound Systems and Technology Group Spanish National Research Council GSTU-CISC Madrid SpainGrupo de Fsica Nuclear Universidad Co

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Document on Subject : "MUBI MultiModal Ultrasound Breast Imaging Research Platform"— Transcript:

1 MUBI : Multi-Modal Ultrasound Breast Ima
MUBI : Multi-Modal Ultrasound Breast Imaging Research Platform J. Camacho, J. F. Cruza, N. González-Salido, M. Pérez-Liva, J.L. Herraiz, J.M. UdíasUltrasound Systems and Technology Group, Spanish National Research Council (GSTU-CISC), Madrid, SpainGrupo de Física Nuclear, Universidad Complutense de Madrid (GFN-UCM), Madrid, Spain REFLECTIVITY IMAGESINTRODUCTIONUSCT IMAGES [1] ARTEMIS project “Advanced Real-TimEMultimodality Medical Imaging”, Comunidadde Madrid, S2009/DPI-1802. [2] TOPUS project “Positron emission and ultrasound tomography”, Comunidadde Madrid, S2013/MIT-3024.[3] J. Camacho, L. Medina, J.F. Cruza, J.M. Moreno, C. Fritsch, "Multimodal ultrasonic imaging for breast cancer detection" Archives of Acoustics, 37-3, 253-260, 2012.[4] L. Medina, J. Camacho, C. Fritsch, "A characterization of ultrasonic full angle spatial compounding as a possible alternative for breast cancer screening" Archives of Acoustics, 40, 3, 301-310, 2015.[5] NuriaGonzález-Salido, Luis Medina, Jorge Camacho, "Full angle spatial compound of ARFI images for breast cancer detection", Ultrasonics, 71, 161-171, 2016.[6] M. Pérez-Liva, J. L. Herraiz, N. González-Salido, L. Medina-Valdés, J. Camacho, C. Fritch, J.M. Udías“Ultrasound Computed Tomography for Quantitative Breast Imaging”, Proc. IEEE Global Medical Engineering Physics Exchanges (GMEPE) & Pan American Health Care Exchanges (PAHCE), Madrid, Spain, 4-9 Apr. pp 1-6, 2016. CONCLUSIONSREFERENCES The Multimodal Ultrasound Breast Imaging System (MUBI) is a joint development of the Spanish National Research Council (CISC) and the ComplutenseUniversity of Madrid (UCM), under the projects ARTEMIS [1] and TOPUS [2]. It is intended to be a flexible platform for multi-modal ultrasound imaging research, mainly oriented to breast diagnosis [3]. Up to now, the following imaging techniques have been implemented:The system is formed by two arrays that rotate into a water tank, controlled by independent stepper motors. A full parallel ultrasound system is used for excitation and signal acquisition.While only one array can be used as emitter, both of them can act as receivers, allowing pulse-echo and through-transmission operation modes. The system is able to perform emission and reception beamformingin real-time, and also gives access to the individual signals received by each array element). A standard personal computer controls the motors movement and the ultrasound equipment with Matlabscripts.MUBI system (left) picture (right) fan-beam acquisition schemeFull Angle Spatial Compound (FASC) of phased-array sector-scan images reduces texture speckle, improves contrast-to-noise ratio (CNR) and reduces direction dependant artifacts like shadows and reverberations. Moving the sample in the vertical direction, a 3D image of the breast can be obtained by slices stacking. An automated algorithm was developed for detecting the breast contour and correcting the beam propagation path before the scan conversion to rectangular coordinates. Phased-Arrayfull angle spatial compound (FASC) [4].Acoustic Radiation ForceImaging (ARFI) full angle spatial compound [5].Ultrasound Computed Tomography(USCT) speed of sound and attenuation reconstruction [6].The MUBI platform has proven to be a flexible experimental tool for research in breast ultrasound. Several imaging modalities have been successfully implemented and tested with tissue mimicking phantoms. Future developments include a second hardware version with a complete ring of 16 arrays, reducing acquisition time by eliminating the circular movement. Emitter Fan-BeamAngle( Receiver(Position2)Receiver(Position1)Receiver(Position3) ARRAYS (Prosonic, Korea) FrequencyElementsPitchP2-4/303.2 MHz1280.22L3-8/405 MHz1280.3048 ULTRASOUND EQUIPMENT (Dasel, Spain) Nºof channels128Excitation100 V square pulse (16 bits coded optional)Bandwidth800 kHz to 16 MHzSampling 40 MHz @ 12 bitsMemoryUp to 4 kSamplesper channelBeamformingDynamic Depth Focusing (DDF)Delay resolution3.125 ns System parameters Turn Radius95 mm (50 mm with optional array holders)Angle resolution0.1 ºZ movementManual screw for sample platform movement SAISAISAISAIFASCSAI : Single Angle Image SAI from45ºFASC with36 images 3D imagewith50 slices ARFI IMAGES Acoustic Radiation Force Impulse (ARFI) images has the ability of discriminating tissue stiffness, a parameter directly relatedwith cancer malignity. We have developed full angle spatial compound algorithm specific for ARFI images, including depth, angle and focal length equalization of individual displacement images. A peculiarity of this work is that ARFI images are acquired without direct contact between the transducer and the breast, which required to account for the water-path in the radiation force generation procedure.Full Angle Spatial Compound of Phased-array images m Soft backbround Hard inclusion Needles FASC Reflectivity ImageFASC ARFI Image Full Angle Spatial Compound of ARFI imagesDataset for USCT reconstruction is available at*: http://ipeusctdb1.ipe.kit.edu/~usct/challenge/?page_id=183 (*) The provided MUBI USCT data is freely available dual licensed under the 3-clause BSD-license and the “Open Data Commons Attribution License”, requiring only acknowledgment / attribution . See more : Ultrasound computed tomography (USCT) is an emerging imaging technique that provides quantitative information of soft-tissues in-vivo. The most common properties obtained with USCT are the speed of sound, which correlates well with the density of the tissue [6] and the acoustic attenuation coefficient which is far more sensitive to the particular tissue type and itmay be used to improve the detectabilityof malignancies. A.Bent rays algorithm using FMM [6] B. Sound speed. C. Reflectivity D. Attenuation ABCD mm/dB/MHzcm