Emma A Meagher MD Director ITMAT Education Programs Program Director MSTR Definition of Clinical Research The Research Landscape Overall Goals of MSTR Program Prepare trainees to think critically to pose and answer research questions ID: 1040495
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1. Master of Science in Translational ResearchEmma A. Meagher, MDDirector, ITMAT Education ProgramsProgram Director, MSTR
2. Definition of Clinical ResearchThe Research Landscape
3. Overall Goals of MSTR ProgramPrepare trainees to think critically to pose and answer research questionsProvide a mentored training experience in translational research by combining a structured curriculum to support project execution and professional developmentTeam Mentoring
4. MSTR ConcentrationsConnecting the basic science of disease with human medicine Testing discoveries for clinical effectNavigating both business and academic environments during research conduct and evaluate commercialization opportunitiesAdopting informatics methodologies to develop and test hypotheses
5. General Information
6. YearFallSpringSummer1Module 1Module 22Module 2Module 4Module 43Module 4Apply to programModule 5Step 1 USMLE Matriculate into MTR July (during Summer Session II semester)Research & course work4MTRResearch & course workMTRResearch & course workMTRResearch & course work5MTRResearch & course workModule 5 Complete research Integration of Curricula – Sample Study Plan
7. MSTR CurriculumMSTR First YearProfessional Skills Development Program (Years 1 & 2)Summer Session II FallSpringSummer Session IMTR 6010 Review Writing MTR 6020 Proposal Development MTR 6000 BiostatsMTR 6040 Scientific & Ethical Conduct IRB Membership begins (6 months) MTR Elective 1 MTR 6050 Data Manuscript WritingMTR 9999 Lab 1 MTR 6030Disease Measurement MSTR Second YearSummer Session IIFallSpringSummer Session IIRB Membership cont.MTR Elective 2MTR 9999 Lab 2MTR 6070 ThesisMTR 6080 ThesisThesis Defense Each student is guided by a mentoring team to develop a plan of study tailored to their research project and career interests. Courses are designed with a student-centered approach where students are engaged in group projects and presentations, peer to peer feedback, and case-based discussions.
8. Research Projecttimeline based on a July 2023 matriculationInitial ProposalWritten Thesis &Oral DefenseSpring 2025MTR 602Peer ReviewJuly-Aug2023Late Sept2023Submit Final Proposal 2023 to2025Project ExecutionFaculty Review & Presentation April-June2023Refine ProposalEarly Sept2023
9. Clinical Rotations**MTR 605 Data Manuscript Writing is a required course and is only offered in Year 1, Summer Session IYear 1 MSTR Professional Skills Development Program Summer Session II FallSpringSummer Session IMTR 6010 & 602MTR 6000 & 6030MTR 6040Elective 1 MTR 6050**MTR 9999 Lab 1Year 2 MSTR Summer Session IIFallSpringJuly/August Clinical Rotations PermittedElective 2MTR 9999 Lab 2Thesis Defense (MTR 6070/6080)Jan - AprilClinical Rotations Permitted
10. YearFallSpringSummer1Module 1MD tuition (by semester)Module 2MD tuition (by semester)2Module 2MD tuition (by semester)Module 4MD tuition (by semester) Module 43Module 4 MD tuition (by semester)Module 5MD tuition (by semester)MTR tuition (by course)TL1 Stipend starts July 1st 4MTR tuition (by course)TL1 Stipend MTR tuition (by course)TL1 Stipend MTR tuition (by course)TL1 Stipend ends June 30th 5MTR tuition (by course)Module 5 + MTRMD tuition (by semester) Finances
11. Grant Funding & Tuition CostsAll TL1 scholars receive a cost-of-living stipend of $26,352 for one year, paid monthlyStipend level is set by the NIH each year. Tuition Costs to student$66,600 (Total MSTR degree cost in FY 23, see most current tuition rates)$20,200 in tuition costs is provided by appointment to the TL1 grantSubtract $11,100 (PSOM additional course policy for 2 courses)This leaves $35,300 estimated out of pocket costs for MSTR tuitionThe out-of-pocket tuition cost is roughly equivalent to the one semester of MD tuition that is not charged during Fall of year 5.If you receive a PSOM scholarship, it can not be used during the MSTR program, thus you are taking on an additional financial burden.
12. StudentResearch ProjectMentorAustin BorjaChanges in the dynamical stability of brain activity during different states of consciousnessAndrew G. Richardson, PhDDebanjan HaldarDeveloping Imaging and Liquid Biopsy Biomarkers for Pediatric Brain Tumor Prognoses and Treatment Response.Phillip Storm, MDAdam Resnick, PhDTristan LimInvestigating Immune Mechanisms in FLASH RadiotherapyAndy Minn, MD, PhDKeith Cengel, MD, PhDChristina MurphyTRPA1 activation in mammalian skin regenerationThomas Leung, MD, PhDEllie SellCOVID-19: Elucidating the Role of the Nasal Epithelium in SARS-CoV-2 Infection, Transmission, and PreventionNoam Cohen, MD, PhDSusan Weiss, PhDCurrent MD-MSTR Students
13. ITMAT MS1 Summer Internship OpportunityITMAT offers a seven-week funded summer internship for Penn MS1 students engaging in translational researchApplications for summer 2023 are due February 3, 2023Student spotlights and a list of former interns and projects Questions can be directed to Megan Maxwell at mmaxwell@upenn.edu
14. Next StepsContact ITMAT Ed with any questionsdiscuss research areas of interestmentor selection, program and/or funding logisticsStart to think about areas of research interestCall for applications to the program goes out in Aug/Sept of your 3rd year
15. MSTR Contact InformationEmma A. Meagher, MD, Program Directoremma@upenn.eduMegan Maxwell, MSW, Associate Directormmaxwell@upenn.eduVisit website
16. K23/08/01 Awards 64 Applied47 Awarded1 Pending75% AwardedK23/08 Awards 1 Applied1 AwardedGrant TypeNumber AwardedK23/K08/K0147Other career development19F323R0127R2110R562U013Projects in P/U, Other Federal & International57Foundation125Venture Capital/Accelerators4Pharma/Biotech104MSTR Graduates n=174MSTR Graduate Outcomes 2022