PPT-PRIONS What are PRIONS?

Prions are infectious agents composed of protein in misfolded form initially thought to be viruses which replicated slowly within their hosts but no nucleic acid found associated with infectious material. Web: . pollev.com/. ucibio. Text: . To: 37607. . Type in: 169964 <your question>. The importance of structure. “Chaperones” & protein folding. Misfolded. proteins are very, very bad!. Invasive Diseases. Infectious Disease. Also known as . Contagious Disease. Communicable Disease. Transmissible Disease. Caused by a pathogen that causes disease. Not all infections cause disease that can be transmitted. Infectious Agents of Animals . and Plants. Chapter 14. What am I?. Structure and Classification of Animal Viruses. Classification of animal viruses. Taxonomic criteria based on. Genomic structure. DNA or RNA. Strategies for RMDs. Presented By:. Lon Bruso. Vice President, . SteriTec. Products. Verification of Washing. Quality system basics. Importance of washing verification. Blood residual as a test soil. MAS.S62 FAB. 2. 3.20.12. 0] Autocatalytic Reactions. 1. ] . Nucleotide Systems. 2] Amino Acid systems. 3] Organic Chemical Systems. Atoms: ~ 20 [C,N,O]. Complexion: . W. ~ 3. 20. . x. = 32. Product: C = 4 states. Inherited and transmissible by ingestion, transplant, and surgical instruments. Spongiform encephalopathies: Sheep scrapie, Creutzfeldt-Jakob disease, Gerstmann-Sträussler-Scheinker syndrome, fatal familial insomnia, mad cow disease. Prusiner. MD. 1942-present . KUMC Neurology Morning Report. Richard J. Barohn, MD. May 8, 2017. Stanley B. . Prusiner. Biography. YEAR. ACHIEVEMENT. 1942. Born in . Des Monies IA. 1896 Grandfather emigrated from Moscow to Sioux City, IA. Infection: Results when a pathogen invades and begins growing within the host. Disease: Results only if and when normal tissue function is impaired. The body has defense mechanisms to prevent infection (i.e. burns, skin lesions). Microorganisms. Also called microbes. Cannot be seen without a microscope. May be . non-pathogen . or . pathogen. depending on where it is in body . Microorganisms. Aerobes. are a variety of bacteria that require oxygen to grow. . Carlos Francisco Mendoza. Human Prion Diseases. Comparison of Prp. C. and . Prp. Sc. Evidence Supports the Prion Hypothesis. Genetic . Polymorphism. RPSA Polymorphisms have no direct influence on susceptibility to sporadic CJD. Atif. . Chohan. & Alex . Brown. What is CJD?. Degenerative brain disorder. Uncommon, usually fatal. Appears in older people, short duration. First described in 1920. Hans Gerhard . Creutzfeld. /. For More Information Contact: • NORTH DAKOTA GAME AND FISH DEPARTMENT 100 N Bismarck Expressway Bismarck, ND 58501 701-328-6300 gf.nd.gov – ndgf@nd.gov • BOARD OF ANIMAL HEALTH  Dept. of Biology, 2. nd. year, 2020. Mustansiriyah. University. References:. Virology: principles and applications, John Carter and Venetia Saunders, 2013.. Principles of Molecular Virology, Alan, J. . 2. CNS Infection - Meninges. CNS infections: most are due to sepsis. Pathogenesis:. Hematogenous spread (most common) . Traumatic implantation . Local extension from nearby infection . Ascent of peripheral nerve.