PPT-Heritability Is it all in the GENES?

Discussion Pair and Share What is a personality characteristic talent or skill that runs in your family Who in your family has it Make a little family tree chart depicting it What is the likelihood that the trait is . 4NeoplasticProcessincludesMeSHtermsreferringtocan-cers. SemanticType IntermediateBMeSHTerms G E A Genes,jun 1 Genes,fos 2 Genes,APC 3 Genes,Reporter 4 Genes,Dominant 5 Genes,ras 6 Genes,rel 7 Genes,bc What is . Selection. ?. Mating animals to produce certain characteristics. Low Birthweight. Heavier Weaning Weight. Color. Horned or Polled. Temperment. What makes an animal they way that they are?. Animals are the result of . Lipika. Ray. 4th . June 2010. Heritability:. Phenotype (P) = genotype (G) + environmental factors (E). (observed) (unobserved) (unobserved). Variances:. Heritability is defined as ratio of variances, by expressing the proportion of the phenotypic variance that can be attributed to variance of genotypic values:. Chapters 6, 7, and 8. Lecture Notes. Key Question. Are physiological responses a . correlate . of the trait in question, or are they a . cause?. Example: Are shy people shy . because. they have certain physiological responses such as an increased heart rate, or are they shy because of some biological system that makes them that way?. Personality. Nature . v. . Nurture. Nature!. “They are born that way!”. Responsible for ~50% of personality. Nurture!. “It’s their experiences & how they were raised!”. Responsible for ~50% of personality. NATURE VS. NURTURE. Gordon Allport . Founder. of the Trait Theory. Predispositions to respond, in a same or similar manner, to different stimuli. After meeting Freud, . Allport. felt there was too much emphasis on inner drives. New Statistical Approaches. Or . Zuk. . Broad Institute of MIT and Harvard. orzuk@broadinsitute.org. www.broadinstitute.org/~orzuk. Genome . Wide Association Studies (GWAS). 2. l. ength: ~3x10. 9. ACCGAGAGGGTT. . Dorret Boomsma. . Vrije Universiteit Amsterdam. Dept. Biological Psychology. No aspect of human behavior genetics has caused more confusion and generated more obscurantism than the analysis and interpretation of the various types of non-additivity and non-independence of gene and environmental action and interaction . János Réthelyi, . M.D. ., . Ph.D. .. Department of Psychiatry and Psychotherapy. Semmelweis University. September. 18th 2013. Outline. The issue of Gene-Environment Interactions: Why are they important?. 1. Behavior Genetics and Evolutionary Psychology. Behavior Genetics: Predicting Individual Differences. Genes: Our Codes for Life. Twin and Adoption Studies . Temperament and Heredity. Nature . and. Nurture. common . disease. AKA . –. everything is much harder in a binary trait. Naomi Wray. 1. Missing heritability . psychiatric disorders. N cases. N loci. h. 2. SNP-h. 2. Schizophrenia. 67K. 245. 80. 26. Lecture Notes. Key Question. Are physiological responses a . correlate . of the trait in question, or are they a . cause?. Example: Are shy people shy . because. they have certain physiological responses such as an increased heart rate, or are they shy because of some biological system that makes them that way?. Genes and Inheritance. 2017. ggibson.gt@gmail.com. http://www.cig.gatech.edu. Course Outline. 1. Genes and Inheritance (GG). 2. Molecular Biology of the Genome (JL). 3. . Population and Evolutionary Genetics (JL). Associate . Professor. Dept. of Genetics and Animal Breeding. PSTU, . Barishal. campus. Overview. Definition. Scale of Heritability. Example. Uses of Heritability. Limitations of Heritability. Methods of Estimation of Heritability.