A AcademicResearch Program Extent of Lung Resection No of Subject Event Censored Median Survival 95 CI 60 mo Survival Lobectomy 1778 616 35 1162 65 NA 996 NA 736 714 756 ID: 398184
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Slide1
Supplemental Digital Content Figure 1A
A
Academic/Research Program
Extent of Lung Resection
No. of Subject
Event
Censored
Median Survival (95% CI)
60 mo Survival
Lobectomy
1778
616 (35%)
1162 (65%)
NA (99.6, NA)
73.6% (71.4%, 75.6%)
Segmental Resection
130
71 (55%)
59 (45%)
74.6 (58.9, 87.4)
58.8% (49.7%, 66.9%)
Wedge Resection
718
393 (55%)
325 (45%)
71.2 (64, 77)
57.4% (53.6%, 61.0%)Slide2
Supplemental Digital Content Figure 1B
B
Comprehensive Community Cancer Program
Extent of Lung Resection
No. of Subject
Event
Censored
Median Survival (95% CI)
60 mo Survival
Lobectomy
2639
1055 (40%)
1584 (60%)
97.1 (92, 104)
69.2% (67.3%, 71.0%)
Segmental Resection
129
59 (46%)
70 (54%)
85.7 (61.3, NA)
60.1% (50.7%, 68.3%)
Wedge Resection
987
559 (57%)
428 (43%)
66 (59.1, 70)
52.6% (49.4%, 55.8%)Slide3
Supplemental Digital Content Figure 1C
C
Non-Comprehensive Community Cancer Program
Extent of Lung Resection
No. of Subject
Event
Censored
Median Survival (95% CI)
60 mo Survival
Lobectomy
440
176 (40%)
264 (60%)
81.8 (73.8, NA)
64.2% (59.1%, 68.8%)
Segmental Resection
27
17 (63%)
10 (37%)
64.6 (46.3, NA)
61.3% (40.0%, 77.0%)
Wedge Resection
186
92 (49%)
94 (51%)
66.9 (53.8, 75.2)
54.6% (46.3%, 62.1%)Slide4
Supplemental Digital Content Figure 2A
A
Tumor ≤ 1 cm
Extent of Lung Resection
No. of Subject
Event
Censored
Median Survival (95% CI)
60 mo Survival
Lobectomy
722
219 (30%)
503 (70%)
NA (104.6, NA)
76.7% (73.3%, 79.7%)
Segmental Resection
51
21 (41%)
30 (59%)
94.9 (58.9, NA)
64.1% (48.7%, 75.9%)
Wedge Resection
439
208 (47%)
231 (53%)
82.9 (75.4, 89.4)
61.2% (56.3%, 65.8%)Slide5
Supplemental Digital Content Figure 2B
B
Tumor 1 – 2 cm
Extent of Lung Resection
No. of Subject
Event
Censored
Median Survival (95% CI)
60 mo Survival
Lobectomy
4135
1628 (39%)
2507 (61%)
96.9 (93.2, 99.7)
69.3% (67.8%, 70.7%)
Segmental Resection
235
126 (54%)
109 (46%)
73.5 (64.6, 79.9)
58.7% (52.0%, 64.8%)
Wedge Resection
1452
836 (58%)
616 (42%)
64.4 (59.9, 68.3)
52.7% (50.0%, 55.3%)Slide6
Supplemental Digital Content Figure 3A
A
Regional Lymph Nodes Examined ≤ 7
Extent of Lung Resection
No. of Subject
Event
Censored
Median Survival (95% CI)
60 mo Survival
Lobectomy
2881
1126 (39%)
1755 (61%)
98.5 (92.2, 108.2)
69.1% (67.3%, 70.8%)
Segmental Resection
246
125 (51%)
121 (49%)
74 (65.7, 89.3)
60.3% (53.8%, 66.3%)
Wedge Resection
1739
974 (56%)
765 (44%)
66.3 (62.2, 70.2)
53.8% (51.3%, 56.2%)Slide7
Supplemental Digital Content Figure 3B
B
Regional Lymph Nodes Examined > 7
Extent of Lung Resection
No. of Subject
Event
Censored
Median Survival (95% CI)
60 mo Survival
Lobectomy
1976
721 (36%)
1255 (64%)
100.6 (97.1, 110)
72.3% (70.2%, 74.3%)
Segmental Resection
40
22 (55%)
18 (45%)
69.5 (49.8, NA)
54.8% (37.5%, 69.1%)
Wedge Resection
152
70 (46%)
82 (54%)
79.6 (69.1, 97.7)
64.4% (55.9%, 71.8%)Slide8
Supplemental Digital Content Figure 4A
A
Negative Surgical Margins
Extent of Lung Resection
No. of Subject
Event
Censored
Median Survival (95% CI)
60 mo Survival
Lobectomy
4783
1810 (38%)
2973 (62%)
99.7 (96.9, 105.3)
70.5% (69.1%, 71.8%)
Segmental Resection
280
144 (51%)
136 (49%)
74 (65.7, 87.4)
59.6% (53.4%, 65.2%)
Wedge Resection
1797
983 (55%)
814 (45%)
68.8 (64.8, 72.2)
55.2% (52.8%, 57.6%)Slide9
Supplemental Digital Content Figure 4B
B
Positive Surgical Margins
Extent of Lung Resection
No. of Subject
Event
Censored
Median Survival (95% CI)
60 mo Survival
Lobectomy
74
37 (50%)
37 (50%)
85.4 (62.7, 100.8)
66.1% (53.8%, 75.9%)
Segmental Resection
6
3 (50%)
3 (50%)
65.1 (18, NA)
60.0% (12.6%, 88.2%)
Wedge Resection
94
61 (65%)
33 (35%)
43.1 (31.5, 63.9)
43.7% (33.3%, 53.6%)