PPT-  Precision Medicine For Aggressive Lymphoma

PMAL Consortium and Associated Trials 2016 CONFIDENTIAL The new name for Leukaemia amp Lymphoma Research Tackling Diffuse Large Bcell Lymphoma 2 Clinical Problem Standard of care RCHOP results in cure rates around 75. Lymphoma is divided into two major categories Hodgkin lymphoma HL and nonHodgkin lymphoma NHL Mantle cell lymphoma MCL is one of about 70 di64256erent subtypes of NHL Lymphoma may arise in any one of three types of lymphocytes B lymphocytes B cells 1 02 03 04 05 06 07 08 09 1 Measured Value of x Fraction of Total Measurements SD 01 SD 02 SD 03 brPage 5br mean standard deviation histogram Figure 3 Mass of Unknown Sample 102 104 106 108 11 112 114 116 118 12 Mass kg of Measurements brPage 6br IRIA- 1192. Case Discussion. A 46 year old male with complaints of. . -. Dysphagia. x 2 weeks. . -. Epigastric. Pain x 2 weeks. . -Vomiting x 40 hours. An upper gastrointestinal endoscopy was done which revealed a gastro-duodenal junction growth invading the . Common (West), low-grade B-cell lymphoma. Affects elderly. Arises from germinal center B-cell. Lymphoma cells have specific translocation t(14:18), in which Bcl2 gene on chr18 fuses with . IgH. gene on chr14, causing . Virginia C. . Broudy. , MD. September 25, 2014. Presentation prepared by: . Presenter. Last Updated: . Date. AIDS-Defining Malignancies. Kaposi sarcoma . NHL – now has a higher incidence than Kaposi Sarcoma in the US. and their . precursor . cells. .  The name often refers to just the . cancerous. . ones . rather than all such . tumors. .. Many lymphomas are known to be due to specific genetic mutations.. 3. rd. a closer look . SEER HEMATOPOIETIC DATABASE. Understanding the disease. AMBIGUOUS TERMS. Choosing . the right . Histology & TOPO CODE . Navigation of the Hematopoietic and Lymphoid Neoplasm Database . Mariko Yabe, MD. PhD, Guilin Tang, MD. PhD, . Ken . H. Young, MD. PhD, Sa A. Wang, MD. .. Department of Hematopathology, . UT . MD Anderson Cancer Center, . Houston. , Texas, USA. Case: 57 year-old Caucasian . Prof Ivy A E . Ekem. 16. th. September 2016. Blood. en.wikipedia.org / M. . Komorniczak. . Accessed 08.09.16. Development of blood cells. en.wikipedia.org. Site of blood formation. www.healthline.com>Ref Library. L, FILIPPAP, MOWAN. Primary nasal paranasaloropharyngeal lymphoma in the pediatric agegroup. Cancer 1990; 65: 1438-1444.YP, SYW,XF, ZXH, LRadiotherapy As Primary Treatment for stage IEand IIE nasal na This is a controlled document and therefore must not be changed or photocopied L.13 High dose METHOTREXATE (high grade NHL CNS prophylaxis) Authorised by Lymphoma lead Dr. Graham Collins Date: M 1 AN UPDATE OF PATHOGENETIC FEATURES WCRJ 2016; 3 (2): e715 INTRODUCTION Extra-nodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue represents approximately 8% of all non-Hodgkin 1 Department of Pathology and Hematopathology, St. Jude Children's Research Hospital, Memphis, TN;Department of Pathology, Division of Hematopathology, University of Miami, Sylvester Comprehensive Can Owen Tan. 1. , Deborah Schofield. 1. , Rupendra Shrestha. 1. 1. GenIMPACT: Centre for Economic Impacts of Genomic Medicine, Macquarie Business School, Macquarie University, Australia.. Presenting at: .