PPT-Virology Introduction to viruses

Viruses consist of a nucleic acid either DNA or RNA associated with proteins encoded by the nucleic acid The virus may also have a lipid bilayer membrane or envelope but this is acquired from the host cell usually by budding through a host cell membrane If a membrane is present it must contain one or more viral proteins to act as . Virology. Biology 516 Fall. Virology. Virology: is . the study of . viruses. . M. icroscopic. , parasitic particles of genetic material contained in a protein . coat.. Viruses . must. be within a host cell to reproduce.. Introduction to Basics . Dr.T.V.Rao MD. Dr.T.V.Rao MD. 1. History Virology. Smallpox was endemic in China by 1000BC. In response, the practice of . variolation. was developed. Recognizing that survivors of smallpox outbreaks were protected from subsequent infection, variolation involved inhalation of the dried crusts from smallpox lesions like snuff, or in later modifications, inoculation of the pus from a lesion into a scratch on the forearm of a child. . Introduction to viruses . Viruses consist of a nucleic acid (either DNA or RNA) associated with proteins encoded by the nucleic acid. The virus may also have a lipid . bilayer. membrane (or envelope) but this is acquired from the host cell, usually by budding through a host cell membrane. If a membrane is present, it must contain one or more viral proteins to act as . Dr. Sinan Bahjat . M B . Ch. B, M . Sc. , F I B M S. Virology. is the science that is concerned with the study of viruses. . In . 1898, . the two scientists . Loeffler. . and . Frosch. . found evidence that . part 3. ..\practical virology\virology\lab.10\cell culture video.mp4. Since the discovery by Enders (1949) that polioviruses could be cultured in tissue, cell culture has become a very useful and convenient method for isolating viruses in vitro. . Virology lecture 3. . . Dr. . Sadia. . Anjum. Entry of avian . leukosis. virus . (a model, simple, retrovirus). Classically all retroviruses were thought to be pH-independent. More recently ALV has been proposed to require low pH, but in addition to its receptor-induced conformational change. - Classification of viruses . - Replication of viruses . . Virology . Virology: is a branch of science . that deals with viruses and viral . diseases.. Viruses are the smallest infectious. Pass through specially designed filters. . In 1935, W.M Stanley – isolated TM V – find properties of a crystalline solid . . . Virus not a simply protein but nucleoprotein . Its infectious principle is the nucleic acid (RNA/DNA). to virology. What is a Virus?. Viruses are infectious units with diameters of about 16 nm to over 300 nm (poxviruses). Their small size makes them ultra filterable, i.e. they are not retained by bacteria-proof filters. Viruses have evolved over longtime period, and have adapted to specific organisms or their cells. The infectious virus particles, or . Ori. Disclaimer. The information represents my understanding only so errors and omissions are probably rampant. It has not been vetted or reviewed by faculty. The source is our class notes.. The document can mostly be used forward and backward. I tried to mark questionable stuff with (?). . . By. Prof. Dr. Abdul-Hameed Khalid . Khadhair. . Medical Virology:. - Introduction. - History and Technology Development. - Theories on origin of viruses. - Viruses and virus-like structures. History of Viruses:. Dept. of Biology, 2. nd. stage, 2016-2017. 2. nd. semester. References. :. Virology: principles and applications, John Carter and Venetia Saunders, 2013.. Principles of Molecular Virology, Alan, J. . Topics. Week l:. -Introduction and General characters of viruses. . (History ,definition, and importance of study). . Viral . structure. Virus . structure and morphology. composition . General characters of viruses. :. Virus . particles are very small in size; they are between 20-500 nm (nanometer) in . diameter. For this Viruses . cannot be seen by ordinary microscope, but only by Electron microscope (EM)..