PPT-PART II: Recombination and selection

Summary of assumptions so far We have covered the role of chance parent choice demography population size and mutation in shaping genetic diversity Neutral WrightFisher models Parents are always chosen at random This means no new mutations affect reproductive success of parents ie . Jelle Kaastra. with. . Ton . Raassen. , . Liyi. . Gu. , . Junjie. Mao, . Igone. . Urdampilleta. , . Missagh. . Mehdipour. SRON & Leiden University. Introduction. X-ray emitting plasmas everywhere:. Zhi. -Ming Ma. . ECM2013 . PolyU. . Email: mazm@amt.ac.cn . http://www.amt.ac.cn/member/mazhiming/index.html. A New Method for Coalescent Processes with Recombination . nanocrystals. doped with P, Li, S. N.V. . Derbeneva. , . V.A. . Burdov. Lobachevsky. State University of Nizhniy Novgorod. Published data . by other authors . on . radiative. recombination lifetimes. HORT6033. Molecular . Plant . B. reeding. Instructor: Ainong . Shi. HORT6033 web site: . http://comp.uark.edu/~ashi/MB. . Fall 2014 HORT6033. Molecular Plant Breeding. Lecture 9 . (09/22/2014). Genetic map construction. Secreted by B lymphocytes. Great diversity and specificity: >10. 9. different antibodies; can distinguish between very similar molecules. Tag particles for clearance/destruction. Protect against re-infection (vaccines). Chromosome mapping by recombination . Meiosis is the basis of transmission genetics. The recombination that occurs during meiosis (in heterozygotes) generates data that are a useful tool for making linkage maps. Different . recombinases. have different topological mechanisms:. Xer. . recombinase. on . psi. .. Unique product. Uses topological filter to only perform deletions, not inversions. Ex: . Cre. . Alexei Fedorov. Recombination is an intrinsic property of nucleic acids and these molecules are susceptible to joining their ends. .. Evolution invented thousands of proteins that assist DNA recombination and became crucial for cell functioning. . Drosophila . pseudoobscura. species group. Mohamed A. F. Noor. Duke University. EVOLUTION:. Two fundamental processes. Change within . lineages (adaptation important). Form new lineages . (speciation important). Jelle Kaastra. with. . Ton . Raassen. , . Liyi. . Gu. , . Junjie. Mao, . Igone. . Urdampilleta. , . Missagh. . Mehdipour. SRON & Leiden University. Introduction. X-ray emitting plasmas everywhere:. Discovery. Genetic linkage was first discovered by the British. . geneticists William Bateson, Edith Rebecca Saunders and Reginald Punnett. . shortly after Mendel's laws were rediscovered. The understanding of genetic linkage was expanded by the work of Thomas Hunt Morgan. . Pairs of allelic genes may exchange chromosomal locations( genetic elements can move, both between chromosomes and within them.) by a process known as genetic recombination.. Homologous recombination . R. ecombination. 2. . Site-Specific . R. ecombination. 3. DNA . Transposition. Homologous Recombination at the Molecular Level. DNA BREAKS ARE COMMON AND INITIATE RECOMBINATION. Recombination repair DNA breaks by retrieving sequence information from undamaged DNA. General background to site-specific recombination . The lambda recombination system (more stealing from other organisms!). Potential advantages of using recombination for cloning. Adaptation of the lambda recombination system for efficient cloning – GATEWAY technology.