PPT-Genetic and Chromosomal Abnormalities

Human chromosomes Most cells in your body normally contain 46 chromosomes organized into 23 pairs In each of these 23 pairs youve inherited one chromosome from your father and one from your mother . 405 O Impacto das Altera Abnormalities in Chromosomal Number. Abnormalities in Chromosomal Structure:. Rearrangements. Fragile Sites. Define:. nondisjunction. polyploidy. aneupoidy. trisomy. monosomy. Abnormalities in chromosomal number. Infertility in the Mare. Introduction. Extrinsic Factors. Lack of Use. Sub-fertile Stallion. Poor management. Intrinsic Factors. Many, many, many. Age. Reported to have the most significant bearing on reproductive performance. Istanbul. . International. . Hospital. IVF . Center. Is . aneuploidy. . screening. an . efficient. . tool. in . embryo. . selection. ?. Best. . embryo. Symmetrical. . PNs. . with. . equal. Numerical Abnormalities . . Structural Abnormalities . Numerical Abnormalities . Gains and losses of whole chromosomes in the karyotype string are usually denoted by the use of either a plus ( ) or minus (−) sign before the aberrant chromosome; for example, . blastocyst. is . partially embedded . in the endometrial . stroma. .. In the area over the . embryoblast. , the . trophoblast. has differentiated into two layers:. (. a) an inner layer of . mononucleated. © Taylor & Francis 2015. ROLE OF GENES AND CHROMOSOMES. A zygote is a single fertilized cell.. A somatic cell is a body cell. . A germ cell is a sex cell. . Cell structure includes a cell membrane that surrounds the cell material (cytoplasm). The nucleus in the center of the cell houses the chromosomes.. Gabr. Objectives. By the end of this lecture, the student should be able to:. 1- Define birth defects. 2- List the causes of birth defects. 3- Define congenital anomaly and the difference . betw. . . Lecturer . Dr. Samah A. Jassam BSc MSc PhD . MRSB. Al-Mustansiriya University . Collage of Pharmacy. What is the secret behind the . transmission of hereditary characteristics from generation to . . sami. FICOG. CABCOG. Recurrent miscarriage. Definition :. ≥ 3 consecutive losses of clinically recognized pregnancies < 20 week gestation. Ectopic, molar, and biochemical pregnancies not included. Dr.Dianatpour. Medical Geneticist. Prenatal tests. Invasive. Karyotype. FISH. QF PCR. Array CGH. Noninvasive. NIPT. Karyotyping. Chromosome Preparation . Any tissue with living nucleated cells that undergo division can be used for studying human chromosomes. Most commonly circulating lymphocytes from . 1 1 . No. 3 . pp: 201 - 208 , March 201 3 Original a rticle The study of chromosomal abnormalities and heteromorphism in couples with 2 or 3 recurrent abortions in Shahid Beheshti H ospital of Ham Department of Zoology. Govt. P.G. College for Women, Gandhinagar, Jammu. . Structural Chromosomal Aberrations. Chromosomal. . aberrations. . are. . substantial changes. . in. . chromosome. . structure and number. Asmaa A. Almukhtar .PHD . Lecturer . Medical Genetic Department. ICCMGR. 2023. Introduction to Chromosomal Analysis. Reading &Writing a Chromosomal Analysis Report. How to write the chromosomal analysis report?.