PPT-Mutations Learning Goal: Identify mutations in DNA (point mutation and frameshift mutation

The types of proteins an organism possesses depend upon the sequence of nucleotides The two main types of gene mutations include Point mutation one base pair is replaced for another base pair. DNA Polymerase can replicate DNA at a rate of . 50,000 base pairs per minute. !. That’s pretty fast – do you think it ever makes mistakes?. Mutations. Mutations. Changes in the genetic code. They come from mistakes that cells have made in copying their own DNA. . Mutations are changes in the genetic material. . Mutations may be genetic mutations or chromosomal mutations.. Genetic Mutations occur in the “code” on DNA or mRNA. Mistakes in . copying the DNA :. GENETIC MUTATIONS. MISTAKES IN DNA. A MISTAKE CAN BE:. 1. A point mutation – substitution, addition, or removal of a single DNA base.. 2. A . frameshift. mutation – . a point mutation due to an addition . Jessica Hawley. Compiled . By: . C. Kohn, Waterford, WI. Objectives. Identify and analyze impacts of mutation.. Interpret impacts of mutation.. Analyze genetic information to determine mutations.. Work on SAE Record Books.. What happens if there is a mistake (. mutation. ). in the DNA code?. Possibly proteins won’t be made or are made improperly.. If the mutations occur in the gametes, the offspring’s DNA will be affected positively, negatively, or neutrally.. Changes in the genetic material. Mutations can occur in two different types of Cells:. 1. Somatic (body) cells. 2. Gamete (sex or germ) cells. Mutations in somatic cells. Usually result in killing that body cell only.. How does it happen???. Environmental Influences . such . as: . Chemicals or UV Rays. Inherited: mutations can be passed down from . parent. to . offspring. During copying of . DNA. , . mistakes. can occur. Understand how they occur. Analyze the different types of mutations. Understand how mutations affect amino acid sequences and proteins. Objective. Central Dogma. DNA is transcribed into RNA, RNA is translated into proteins. Small-scale mutations. Missense mutations. Nonsense mutations. Silent mutations. Frameshift mutations. Large scale mutations. Causes. Mutagens. The results of mutation. Mutations. Genetic mutations are changes in the DNA sequence, caused by various mechanisms.. permanent change . in the DNA sequence of a gene. .. . Mutations . in a . gene's DNA sequence. can alter . the amino acid sequence . of the . protein. encoded by the gene.. GOOD BAD NEUTRAL. Main idea: Gene expression is regulated by the cell, and mutations can affect this expression. Gene Regulation . Cells have the ability to control which genes are transcribed and when they are transcribed. MISTAKES IN DNA. A MISTAKE CAN BE:. 1. A point mutation – substitution, addition, or removal of a single DNA base.. 2. A . frameshift. mutation – . a point mutation due to an addition . or deletion of a DNA base that causes a major change in the genetic code.. Warm up . What are the different types of mutations? How are mutations related to evolution?. Place your warm up in the center of the table.. Place your Lab Evidence Packet (with the essay rubric) in the center of the table.. mutation. Mutations. Ectrodactyly. Progeria. Hypertrichosis. Severe Combined Immunodeficiency Disorder (SCID). Sickle Cell Anemia. Heterochromia. iridium. What is a mutation?. @A . mutation is any change in a cell’s .