PPT-Multi-Scale Mathematical Models of Airway Physiology to Facilitate Cystic Fibrosis Treatment

Modular biophysicallyinspired models can help elucidate Cystic Fibrosis CF airway pathophysiology across multiple scales and provide a bridge from the benchtop to the clinic What is new inside . Treatment . of Cystic Fibrosis. Rebekah F. Brown, MD. Center Director, Cystic Fibrosis Center at Vanderbilt. Objectives. At . the end of this presentation, participants will have an understanding of the pathophysiology of cystic fibrosis and targets of treatment for children and adults with cystic fibrosis.. Vaughan Somerville. Who am I. Heel Prick. Sweat Test. Heel Prick. Diagnosis. Effects 1 in 2500 people. ~ 450 people in NZ. Average life expectancy 37-40. 97% of males are in fertile. What is Cystic Fibrosis (CF). Broadening Your Health Care Team . Meredith Wiltsie, MN, ANP, FNP . Nurse Practitioner, adult Cystic Fibrosis program. Cystic Fibrosis Education Day. March 11. th. , 2017. No disclosures. If you are a CF Center patient, why do you need a Primary Care Physician? . B. oyle. Other names for cystic fibrosis are CF, Pancreas fibrocystic disease, and Pancreatic cystic fibrosis. The name was chosen because.  . cystic . means biliary . area . and fibrosis refers to the scarring of the tissue. So Cystic Fibrosis means tissue scarring of the biliary . Module 1: Cystic Fibrosis Overview. Learning Objectives. Describe the pathophysiology of cystic fibrosis, and specifically how the disease process alters nutrient digestion, absorption, and metabolism.. . Single gene . Mendelian. disorder. Gene codes for the Cystic Fibrosis . Transmembrane. Conductance Regulator protein (CFTR). Daniel R. . Taub. and Joshua Page. Cystic Fibrosis: Exploration of evolutionary explanations for the high frequency of a common genetic disorder.. by. Kathleen A. Nolan and Allen J. . Burdowski. . Biology . and Health Sciences. St. Francis College, Brooklyn, NY. NATIONAL CENTER FOR CASE STUDY TEACHING IN SCIENCE. Students, before coming to class you should have:. Lack of /insufficient surfactant. Alveoli developing. Smaller airways. Underdeveloped cartilage. F. 1. Key Differences (cont). Obligatory nose breather (infant). Intercostal muscles less developed. Faster respiratory rate. Table of Contents Presentation 5 Presentation Resources 6-7 Teacher/Faculty Curriculum 8-9 Teacher/Faculty Resources 10 K-2nd Grade Activities/Materials 11 3rd-5th Grade A Director Dell Children’s Medical Center CF Center. October 28, 2017. Objectives. Pathophysiology of CF. Genetics of CF. Diagnostic evaluation for CF. Respiratory issues in CF. GI and nutrition issues in CF. Nursing College. Cystic Fibrosis. Inherited—. autosomal. recessive. Both parents must be carriers. Each child has a 1 in 4 chance of being affected. Affects primarily white children. Father Mother. ObjectivesUnderstand the genetic abnormality causing cystic fibrosis (CF) and the newborn screen processRecognize the multiple organ systems affected by CFIdentify common treatments /medications and m Hasan NA, Davidson RM, Epperson L, Kammlade SM, Beagle S, Levin AR, et al. Population Genomics and Inference of Mycobacterium avium Complex Clusters in Cystic Fibrosis Care Centers, United States. Emerg Infect Dis. 2021;27(11):2836-2846. https://doi.org/10.3201/eid2711.210124. Dr. JP Jarczyk, MD. February 11, 2023. Disclosures. I have no conflicts of interest to disclose. Objectives. Understand basic genetics of CF. Understand basic pathophysiology of CF. Understand treatments for pediatric patients with CF.