PPT-Examining the Role of Diacylglycerol in the Protein Kinase C Pathway in Lipid-Induced

Author : valerie | Published Date : 2022-06-20

By Samhitha Dhandamudy Goal of Experiment To test whether the presence or absence of calcium ions by blocking the calcium ion channel with statin will impact diacylglycerols

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Examining the Role of Diacylglycerol in the Protein Kinase C Pathway in Lipid-Induced: Transcript

By Samhitha Dhandamudy Goal of Experiment To test whether the presence or absence of calcium ions by blocking the calcium ion channel with statin will impact diacylglycerols ability to activate the protein kinase C pathway which will lead to hepatic insulin resistance . Pierre De . Meyts. = Chuck; . head . of research at Novo . Nordsk. Aug. Insulin. Insulin Receptor. Activates a series of downstream signaling cascades, leading to pleiotropic effects on:. How . does insulin . د. حسين محمد جمعة . اختصاصي الامراض الباطنة . البورد العربي . كلية طب الموصل . 2010. Key points. Consensus guidelines exist for lipid management. Pratt & . Cornely. , Chapter 10. Terms for Signal Transduction. Ligand (first messenger). Receptor (transducer). Primary Effector. Second . messenger. Second effector, etc.. Target proteins/DNA. Ligands. Kinections. Map P36507. MEK2/MAP2K2. P36507. -T230. -S216. +S226. +S222. B-. Raf. P15056. COT/MAP3K8. P41279. PDK1/PDPK1. O15530. MORG1. Q9BRX9. SGK1. O00141. BMAL1. O00327. T484. KRT8. P05787. S74. Fat and Glycerophospholipid Synthesis. 1. 2. 3. 1. 2. 3. 1. 2. 3. Phosphatidic . Acid. Glycerol-3-P. Fat (Triacylglycerol). Glycerophospholipids. Fat Breakdown. Signaling. Catalysis. Glycero. Phospho. BIOCHEMISTRY. Basic Characteristics Of Cell Signaling . Cell must respond appropriately to external stimuli to survive.. Cells respond to stimuli via cell signaling. Each cell is programmed to respond to specific combinations of extracellular signal molecules. BIOCHEMISTRY. Basic Characteristics Of Cell Signaling . Cell must respond appropriately to external stimuli to survive.. Cells respond to stimuli via cell signaling. Each cell is programmed to respond to specific combinations of extracellular signal molecules. NJ Maxvold MD . Associate Professor Pediatrics. Children’s Hospital of Richmond-Virginia Commonwealth University. . No Growth occurs during Acute Illness. . . . Focus : Prevent Malnutrition. retardation. SIK2. Smooth . muscle . relaxation. Melanogenesis. SIK2 inhibitor. Anti hair graying. WT. KO. Resistance to. Stroke. Dementia . Skin. whitening. SIK3. glucose/. fatty acid. cholesterol/. Overview. 1. 2. Autocrine. AKA: . Juxtacrine. 3. Endocrine. 4. Paracrine, Autocrine. Nervous. Juxtacrine. 5. Same signal .  Many different effects. Different Receptors. Different Intracellular Events. It serves as two glands in one: a digestive exocrine gland and a hormone-producing endocrine gland. . Functioning as an exocrine gland, the pancreas excretes enzymes to break down the proteins, lipids, carbohydrates in food. . Bayu. Lestari. What will be Impaired in This Patient?. Obese. Insulin Resistance?. Dyslipidemia? (High TG, High LDL, Low LDL). T2DM?. Metabolic Syndrome. High prevalence of metabolic . s. yndrome: relation between glucose and lipid metabolism. Protein . kinase. A . protein . kinase. is a . kinase. enzyme that modifies other proteins by chemically adding phosphate groups to them (. phosphorylation. ). . Phosphorylation. usually results in a functional change of the target protein by changing enzyme activity, cellular location, or association with other proteins. . 1. WB. A. α. -. sin. A30P 10d. α. -. sin. A30P 24h. α. -. sin. A30P 0h. B. C. D. E. F. 0h. 24h. 48h. 10 . days. A11. α. -. Oligomer. OC. α. -. Fiber. α. -. syn. α. -. monomer. 0h. 24h. 48h.

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