PPT-Serum Creatinine and

eGFR Where A re W e Now Dr Mike Bosomworth Lead Clinician Blood Sciences Leeds Teaching Hospitals 16 th April 2013 1 2 Why measure serum creatinine RENAL CLEARANCE Substance cleared by renal excretion clearance Cy . Protein . Nitrogen (NPN) . Concentration. 224 PHL. Lab#5 . Non-protein nitrogen (NPN). NPN includes . the nitrogen from all nitrogenous substances . other than proteins. ..  . The NPN could be measured as a . Creatinine. . and . eGFR. . Where . A. re . W. e Now?. Dr Mike Bosomworth. Lead Clinician - Blood Sciences. Leeds Teaching Hospitals. 16. th. April 2013. 1. 2. Why measure serum . creatinine. ?. RENAL CLEARANCE. Definition of CKD. Staging of CKD. Etiology of CKD. How to measure Kidney function . Incidence of ESRD. (per million population, 1990, by HSA, unadjusted). USRDS, 2000. Incidence of ESRD. (per million population, 2000, by HSA, unadjusted) . . Functions. Renal function tests; . Why. needed?. When should we assess renal function?. Older. . age. Family . history . of . Chronic . Kidney . disease. . (CKD). Decreased renal. . mass. Diabetes . . creatinine. in serum or . heparinized plasma or urine by a colorimetric . Kinetic . method. Definition. Creatinine. . an anhydride of . creatine. , is a waste product . excerted. by the . kidneys . CREATININE. CLEARANCE. URIC ACID. Mohammed Al-Zubaidi, PhD. Laboratory Training. Introduction. The kidneys are two bean shaped . organs lying . retroperitoneally. on each side . of the . vertebral column slightly above . Objectives:. To have a knowledge about functional units and normal functions of the kidney.. To have an idea about some examples of renal diseases.. . To know laboratory routine kidney function tests (KFTs).. Minal Desai, MD. Jake . Lagomarcino. , PA. Stephanie . LiVecchi. , PA. Betty Masten, MD. Meagan Puckett, FNP. Click to add text. POC CHEM8 . POC BMP Includes: . Ionized Calcium. Potassium. Sodium. Glucose. INENED UE The TREchemie Creatinine ts for te quantttve detrmination ofCreatinine in srum or lasa r rine. INRODCTIO Creatinine iste ctbolcproductofcreatie phosphate,whic isused byte skletl musce. The 5 5 DOI: 10.7860/JCDR/2018/36574.12203 Original Article Miscellaneous Postgraduate Education Letter to Editor Short Communication Images in Medicine Experimental Research Clinician’s corner Revie Dr. Haider . Raheem Mohammad. Introduction. The . aminoglycoside antibiotics are widely used for the treatment of severe . gram-negative infections . such as . pneumonia. or . bacteremia. , often in combination with a . . Mitra K. Nadim, M.D., and Guadalupe Garcia-Tsao, M.D.. NEJM Feb 2023. Dr Monet Philipose. The prevalence of patients with diagnosed CKD receiving serum creatinine testing was 57.0% in 2007 and 77.5% in 2020, in a commercially insured patient population. Serum creatinine testing tended to be higher among older patients. The prevalence of patients younger than 60 years receiving serum creatinine testing decreased from 2007 to 2020. Hispanic patients tended to have the lowest prevalence of testing. The prevalence of serum creatinine testing tended to be higher for patients with diabetes than without diabetes. Patients with hypertension were approximately 1.5 times as likely to receive serum creatinine testing than those without hypertension across this time period.. Assumed background knowledge: basic nephron physiology (filtration, reabsorption, secretion).. Q1. If a plasma solute is filtered and not reabsorbed, what happens to it?. Q2. Consider the fate of a given (fixed) amount of a solute delivered to the...