PPT-The basics of AKI and CKD

Dr Jon Murray Consultant Nephrologist James Cook University Hospital Acute Kidney Injury v Chronic Kidney Disease Creatinine 1250 mol l What are the priorities How is the patient Is this single or multiorgan failure. Dr Andrew Stein. Consultant in Renal and General Medicine, UHCW. May 2015. Aims. Anatomy. Function. Definitions. Creatinine, . eGFR. , CKD, AKI. History. Examination. Investigation. Likely Cases. Theme of Lecture: . Pro: Andy Stein. Con: Dan Ford. Chair: Prof. Higgins. Tuesday, 5. th. November 2013, 1-2pm. CSB Room 00067. The expanding definition of CKD is unnecessarily labelling many people as diseased: Summary. on . Chronic . Kidney . Disease. Maria Ferris, MD, MPH. PhD. Associate Professor. Director of the Pediatric Dialysis and Transplant Services. UNC Kidney Center, Chapel Hill, NC, USA. Akash. and his fan club. Josh Exley. Learning Objectives. Acute Kidney Injury. Drugs and the Kidney. Chronic Kidney Disease. Normal Kidney function. Kidney Functions. Excretory function. Filter metabolites, toxins, drugs. Homeostatic function. Program Goals. Hepcidin in Chronic Kidney Disease. Treatment of Iron Deficiency Anemia. Assessment of IV Iron in Patients With Non-Dialysis-Dependent CKD. DOPPS Study. Ferric Pyrophosphate. Phosphate Binders. 2017 . Annual Data Report. Volume 1: Chronic Kidney Disease. 2. vol 1 Figure 7.1 Sources of prescription drug coverage in Medicare enrollees, by population, 201. 5. Data source: Medicare 5% sample. Point prevalent Medicare enrollees alive on January 1, 2015. Abbreviations: CKD, chronic kidney disease; LIS, Medicare Low-income Subsidy; Part D, Medicare prescription drug coverage benefit.. Learning Objectives. Utilize appropriate screening tools, such as GFR and ACR, in order to diagnose and monitor CKD patients.. Classify CKD, based on GFR and albuminuria categories, in order to guide appropriate treatment. . Data Source: National Health and Nutrition Examination Survey (NHANES), 1988–1994, 1999-2004 & 2007–2012 participants aged 20 & older. Whisker lines indicate 95% confidence intervals. Abbreviations: CKD, chronic kidney disease. This graphic also appears as Figure 1.2. A - versible increase in the blood concentra�on of crea�nine and nitrogenous waste products and by the inability of the kidney to regulate �uid and elec - trolyte ho KDIGO Guideline Co-Chairs:. Alfred K. Cheung, MD. Johannes F.E. Mann, MD. Guideline: . Kidney Disease: Improving Global Outcomes (KDIGO) Blood Pressure Work Group. KDIGO 2021 Clinical Practice Guideline for the Management of Blood Pressure in Chronic Kidney Disease. Kidney Int. 2021;99(3S):S1–S87. WHAT IS ACUTE KIDNEY INJURY(AKI) ?. An abrupt . decline in renal . function defined by:. An increase . in serum creatinine > 26.5 umol/l within 48hours or . > . 1.9 times baseline . known or presumed in the last . In CKD and HD patients dysfunction of . immu. ne . sy. stem . a. lterations. . belonge. to . . involv. ing. . i. nnate. and . a. daptive. . i. mmunity. in T and B lymphocytes (. Reduced . T regulatory cells and memory cells and increased innate cells). . Narender Goel et al.. Middletown Medical PC,. Montefiore Medical Center & Albert Einstein College of . Medicine, New York. 4th International Conference on Nephrology & Therapeutics. September . . 20% - 50%. What you should know…. Acute renal failure or Acute kidney injury?. What means AKI?. Most frequent causes involved?. How to identify an AKI?. Where from should start our therapy? . Renal replacement therapy – when to start?.