Dynamic Display of Bioactivity for Regenerative
Description: Dynamic Display of Bioactivity for Regenerative Medicine Challenge: Regenerative medicine by stem cells is potential solution for tissue repair However, regeneration is complex - cellular responses change over: Time attachment
Related Topics
Download Presentation
"Dynamic Display of Bioactivity for Regenerative" is the property of its rightful owner. Permission is granted to download and print the materials on this website for personal, non-commercial use only, and to display it on your personal computer provided you do not modify the materials and that you retain all copyright notices contained in the materials. By downloading content from our website, you accept the terms of this agreement.
Presentation Transcript
slide1. Dynamic Display of Bioactivity for Regenerative Medicine Challenge:
Regenerative medicine by stem cells is potential solution for tissue repair
However, regeneration is complex - cellular responses change over:
Time attachment → proliferation → differentiation
Space bone, nerve, skin differentiation within one tissue
Develop ECM with dynamic spatio-temporal control over epitope display
Dynamic alginate-cyclodextrin surface with dynamic host-guest chemistry:
Allows for dynamic spatio-temporal manipulation of cell activities
Time stepwise exchange of biochemical cues (epitopes) can direct cell activity
Space surface patterns direct cell growth
Surface is functionalizable
Surface can be patterned Ellen Zhuang | The Stupp Group<br>
Regenerative medicine by stem cells is potential solution for tissue repair
However, regeneration is complex - cellular responses change over:
Time attachment → proliferation → differentiation
Space bone, nerve, skin differentiation within one tissue
Develop ECM with dynamic spatio-temporal control over epitope display
Dynamic alginate-cyclodextrin surface with dynamic host-guest chemistry:
Allows for dynamic spatio-temporal manipulation of cell activities
Time stepwise exchange of biochemical cues (epitopes) can direct cell activity
Space surface patterns direct cell growth
Surface is functionalizable
Surface can be patterned Ellen Zhuang | The Stupp Group<br>